Necrotizing fasciitis
MONDO:0004835Necrotizing fasciitis is a serious infection of the skin, the tissue just beneath the skin (subcutaneous tissue), and the tissue that covers internal organs (fascia). Necrotizing fasciitis can be caused by several different types of bacteria, and the infection can arise suddenly and spread quickly. Early signs include flu-like symptoms and redness and pain around the infection site. A prompt diagnosis and treatment are essential.If the infection is not treated promptly, it can lead to multiple organ failure and death. Treatment typically includes intravenous (IV) antibiotics and surgery to remove infected and dead tissue.
7 clinical trials for this condition and its sub-types.
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New Pig-Skin dressing could speed healing of Flesh-Eating wounds
Disease control Recruiting nowThis study tests a special wound dressing made from pig tissue (Cytal Wound Matrix and MicroMatrix) to see if it helps heal wounds from necrotizing fasciitis (a severe flesh-eating infection) faster than standard dressings. Fifty adults with large wounds (at least 30 cm²) will be…
Phase: NA • Sponsor: Benjamin T. Miller • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New dye test could spot Flesh-Eating bacteria in minutes
Diagnosis Recruiting nowThis study tests whether a safe, FDA-approved dye called indocyanine green (ICG) can help doctors quickly tell the difference between a life-threatening flesh-eating infection (necrotizing fasciitis) and a less dangerous skin infection. About 420 adults with suspected infections …
Sponsor: Eric R. Henderson • Aim: Diagnosis
Last updated Jun 27, 2026 11:03 UTC
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New study aims to predict who will survive Flesh-Eating infections
Knowledge-focused Recruiting nowThis study looks at 300 adults hospitalized with rare but life-threatening flesh-eating infections (necrotizing soft tissue infections). Researchers want to find out which early signs and routine lab tests can predict who is most likely to die during their hospital stay. The goal…
Sponsor: University of Cagliari • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC