New dye test could spot Flesh-Eating bacteria in minutes

NCT ID NCT06877793

Recruiting now Diagnosis Sponsor: Eric R. Henderson Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a safe, FDA-approved dye called indocyanine green (ICG) can help doctors quickly tell the difference between a life-threatening flesh-eating infection (necrotizing fasciitis) and a less dangerous skin infection. About 420 adults with suspected infections will receive the dye and have special camera images taken. The goal is to see if the dye's movement through tissue reveals blocked blood vessels, a hallmark of necrotizing infections, enabling faster and more accurate diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: indocyanine green (ICG) dye
What this could lead to: If successful, this could give doctors a fast, accurate way to diagnose necrotizing fasciitis in the emergency room, reducing delays and improving survival.
What could go wrong: This is an early-stage study testing a new use for an existing dye. It may not prove accurate enough across different hospitals or bacteria types, and false results could still occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

necrotizing fasciitis necrotizing soft tissue infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NECROTIZING FASCITIS

Contacts and locations

Locations

Dartmouth-Hitchcock Medical Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
Emory University/Grady Memorial Hospital
RECRUITING

Atlanta, Georgia, 30322, United States
Stanford University
RECRUITING

Stanford, California, 94305, United States
University of California, Los Angeles
NOT_YET_RECRUITING

Los Angeles, California, 90095, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48104, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Pittsburgh Medical Center
NOT_YET_RECRUITING

Pittsburgh, Pennsylvania, 15213, United States
Vanderbilt University
RECRUITING

Nashville, Tennessee, 37235, United States

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