New Pig-Skin dressing could speed healing of Flesh-Eating wounds

NCT ID NCT06857708

Recruiting now Disease control Sponsor: Benjamin T. Miller Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a special wound dressing made from pig tissue (Cytal Wound Matrix and MicroMatrix) to see if it helps heal wounds from necrotizing fasciitis (a severe flesh-eating infection) faster than standard dressings. Fifty adults with large wounds (at least 30 cm²) will be randomly assigned to get either the new dressing or usual care. The main goal is to see how quickly the wound is ready for skin grafting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cytal Wound Matrix and MicroMatrix (a porcine-derived wound dressing device)
What this could lead to: If it works, this could give doctors a better way to treat severe flesh-eating infection wounds, potentially speeding up healing and reducing the need for multiple surgeries.
What could go wrong: This is a small, early pilot study with only 50 people at one hospital. The treatment is made from pig tissue, so people with allergies or objections cannot join. It may not work better than standard care.

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Conditions

The condition(s) this trial relates to.

necrotizing fasciitis necrotizing soft tissue infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NECROTIZING FASCITIS NECROTIZING SOFT TISSUE INFECTION

Contacts and locations

Locations

Cleveland Clinic
RECRUITING

Cleveland, Ohio, 44195, United States

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