Myostatin-related muscle hypertrophy
MONDO:0013598Myostatin-related muscle hypertrophy is a rare condition characterized by reduced body fat and increased muscle size. Affected individuals have up to twice the usual amount of muscle mass in their bodies. They also tend to have increased muscle strength. This condition is not known to cause any medical problems, and affected individuals are intellectually normal. Myostatin-related muscle hypertrophy is caused by mutations in the MSTN gene. It follows an incomplete autosomal dominant pattern of inheritance.
Also known as: MSLHP, muscle hypertrophy
10 clinical trials for this condition and its sub-types.
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Protein power: whey and collagen combo builds stronger muscles and bones
Disease control CompletedThis study tested whether taking whey protein together with collagen peptides helps resistance-trained men build more muscle and bone density than either supplement alone or a placebo. Forty healthy men aged 18–35 who already lifted weights took one of four supplements for 8 week…
Sponsor: Ankara Yildirim Beyazıt University • Aim: Disease control
Last updated Jun 26, 2026 15:24 UTC
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Squats vs hip thrusts: which really shapes the glutes?
Knowledge-focused CompletedThis trial asks whether the barbell back squat or the barbell hip thrust is better for building glute muscle and strength. About 39 young, untrained adults will train twice a week for nine weeks with one of the two exercises. Researchers will measure muscle size with MRI and stre…
Sponsor: Auburn University • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Carbs vs protein: no extra muscle gains found
Knowledge-focused CompletedThis study looked at whether adding extra carbohydrates to a daily protein supplement helps resistance-trained men build more muscle and strength. Twenty-five men took either a protein-only or a protein-plus-carb supplement for 8 weeks each. The results showed no significant diff…
Sponsor: Auburn University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Cuff up, lift light: new study tests Muscle-Building shortcut
Knowledge-focused CompletedThis study tested whether doing light arm exercises with a blood pressure cuff on the upper arm (blood flow restriction) can build biceps muscle as well as lifting heavy weights. Thirty-three healthy young men who had never done arm training before followed an 8-week program. Res…
Sponsor: Mehmet Akif Ersoy University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Light weights, big gains: study shows lifting to failure works wonders
Knowledge-focused CompletedThis study looked at whether lifting light weights (30% of your max) until you can't do another rep builds muscle and strength as well as lifting heavy weights (75% of your max) in healthy young men who don't usually lift. Twenty-two men did leg exercises three times a week for s…
Sponsor: Akdeniz University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Which training method builds more muscle? new study investigates
Knowledge-focused CompletedThis study looked at 30 healthy adults who already lift weights regularly. Researchers compared two training methods: one that adjusts weights based on movement speed (velocity-based) and one that uses fixed percentages of maximum strength. The goal was to see which method leads …
Sponsor: University of Lisbon • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Can kids build muscle like adults? new study tests flywheel vs. weight stack training
Knowledge-focused CompletedThis completed study looked at how children (ages 9-13) and adults (ages 18-50) respond to 12 weeks of resistance exercise using either flywheel or traditional weight stack machines. 91 healthy participants were randomly assigned to one of three groups: flywheel training, weight …
Sponsor: Björn Alkner • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Scientists uncover how muscles grow and shrink at the protein level
Knowledge-focused CompletedThis study looked at how resistance exercise and leg immobilization affect muscle protein production in 15 healthy women aged 18-30. Participants did leg exercises with one leg while the other leg was immobilized. Researchers measured changes in muscle protein synthesis and break…
Sponsor: Queen's University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC