Morbid obesity

This study tests whether a wearable bioimpedance wristband (like a fitness tracker) helps people with severe obesity and knee osteoarthritis improve their body composition—gaining muscle and losing fat—before joint replacement surgery. All participants receive coaching on body co…

This study aimed to see if bariatric surgery or medical weight loss (diet and exercise) helps severely obese patients lose enough weight to safely undergo hip or knee replacement. Only 3 people took part before the study was stopped early. The goal was to get patients to a BMI of…

This study aimed to compare a standard sleeve gastrectomy (removing part of the stomach) with a modified version called N-Sleeve, which adds a wrap around the top of the stomach to prevent acid reflux. The trial was designed for people with severe obesity and GERD, but only 2 pat…

This study tested a special device called the Traxi panniculus retractor, which holds excess belly tissue out of the way during cesarean deliveries. The goal was to see if it could shorten surgery time, improve breathing, and increase satisfaction for both patients and doctors. T…

This study tested whether a 3D ultrasound device (Accuro) helps anesthesiologists place epidural needles for pain relief during labor in women with a BMI of 40 or higher. The device was compared to the standard blind approach using touch. The trial was terminated early, so result…

This study compared two brands of surgical staplers (Covidien and Ethicon) used in sleeve gastrectomy for people with severe obesity. Researchers wanted to see if one device caused fewer complications like bleeding or leaks. The trial was terminated early and enrolled 62 adults, …

This study looked at whether weight-loss surgery can lengthen telomeres, which are caps on our DNA that shorten as we age. Researchers compared telomere length in people with severe obesity who had surgery versus those who did not. The goal was to see if rapid weight loss might r…