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Mediastinitis
MONDO:0004492An inflammatory process affecting the mediastinum.
17 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New stitch and glue combo aims to cut infections after bypass surgery
Disease control Not yet recruitingThis study tests a new method for closing the breastbone after coronary artery bypass graft (CABG) surgery using special knotless barbed sutures and a skin adhesive. Researchers will compare 401 adults who receive this new closure to past patients who had standard closure. The go…
Phase: PHASE4 • Sponsor: Unity Health Toronto • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Antibiotic penetration study aims to improve infection treatment
Knowledge-focused Not yet recruitingThis study looks at how the antibiotic delafloxacin spreads through the body in 20 adults with serious skin, soft tissue, bone, or joint infections. Researchers will measure drug levels in blood and in tissues collected during surgery. The goal is to understand if the drug reache…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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30,000 blood samples could revolutionize rapid disease testing
Knowledge-focused Not yet recruitingThis study will collect blood samples from 30,000 adults in the UK with various health conditions, including blood clots, infections, heart disease, diabetes, and more. The samples will be used to develop and fine-tune new diagnostic tests for the cobas® lumira device, which allo…
Sponsor: LumiraDx UK Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Tiny probe tracks antibiotic in Kids' chests after heart surgery
Knowledge-focused Not yet recruitingThis study looks at how the antibiotic cefazolin spreads in the chest tissue of 10 children after heart surgery for congenital heart disease. A small probe placed during surgery will measure drug levels over 36 hours. The goal is to create a computer model to help doctors give th…
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC