Tiny probe tracks antibiotic in Kids' chests after heart surgery

NCT ID NCT07327502

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how the antibiotic cefazolin spreads in the chest tissue of 10 children after heart surgery for congenital heart disease. A small probe placed during surgery will measure drug levels over 36 hours. The goal is to create a computer model to help doctors give the best dose to prevent infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cefazolin
What this could lead to
If successful, this could help doctors give the right dose of cefazolin to prevent infections after children's heart surgery.
What could go wrong
This is a very small, early study with only 10 children, so results may not apply to all kids. It only measures drug levels, not whether infections are actually prevented.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Necker Enfants Malades

    Paris, Île-de-France Region, 75015, France