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Mediastinitis

MONDO:0004492

An inflammatory process affecting the mediastinum.

6 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Inflammatory disease (341) Human disease (15) Disease by developmental or physiological process (0)
Not yet recruiting 3 Not yet finished but already full! 1 Completed 2
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  • New plasma and gas combo may fight deadly heart surgery infections

    Disease control Completed

    This study tested a combined treatment using air-plasma flow and nitric oxide gas to prevent and treat wound infections after heart surgery. It included 80 patients with mediastinitis, a serious chest infection. The goal was to see if this approach could reduce infection, improve…

    Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences • Aim: Disease control

    Last updated Jun 27, 2026 14:01 UTC

  • Heart surgery patients get faster healing with own blood plasma

    Disease control Completed

    This study tested whether applying a patient's own platelet-rich plasma (PRP) to the chest wound during heart surgery reduces infections and improves healing. 98 adults undergoing bypass surgery were randomly assigned to receive PRP or standard wound closure. Results showed that …

    Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University • Aim: Disease control

    Last updated Jun 27, 2026 09:00 UTC

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