Median nerve neuropathy
MONDO:0003598Disease involving the median nerve, from its origin at the brachial plexus to its termination in the hand. Clinical features include weakness of wrist and finger flexion, forearm pronation, thenar abduction, and loss of sensation over the lateral palm, first three fingers, and radial half of the ring finger. Common sites of injury include the elbow, where the nerve passes through the two heads of the pronator teres muscle (pronator syndrome) and in the carpal tunnel (carpal tunnel syndrome).
Also known as: median nerve peripheral neuropathy, peripheral neuropathy of median nerve, median nerve palsy
33 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New turkish diagnostic tool for carpal tunnel syndrome under study
Diagnosis CompletedThis study aims to translate and test a diagnostic tool called CTS-6 for Turkish-speaking patients with carpal tunnel syndrome. Researchers will enroll 126 adults, including healthy volunteers, people with symptoms, and those already diagnosed. The goal is to ensure the tool is a…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated Aug 01, 2026 00:00 UTC
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Laser test could objectively measure nerve pain for first time
Diagnosis CompletedThis study tested whether a diode laser can act as a biomarker to measure neuropathic pain in people with peripheral neuropathy. Researchers compared pain responses to a lidocaine patch versus a placebo patch in 75 participants. The goal was to see if the laser test could disting…
Phase: NA • Sponsor: University of Utah • Aim: Diagnosis
Last updated Jun 27, 2026 12:09 UTC
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Ultrasound may replace nerve tests for carpal tunnel diagnosis
Diagnosis CompletedThis study tested whether ultrasound can accurately diagnose mild to moderate carpal tunnel syndrome (CTS) by measuring the median nerve. Researchers compared ultrasound results with standard nerve tests and checked how they related to pain, symptoms, and quality of life in 75 pe…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated Jun 27, 2026 09:04 UTC
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Pain education may ease carpal tunnel without surgery
Symptom relief CompletedThis study tests whether pain neuroscience education (PNE) can improve symptoms in people with mild to moderate carpal tunnel syndrome. Participants will receive PNE along with standard home exercises and a wrist splint. The goal is to see if understanding pain better leads to le…
Phase: NA • Sponsor: Karamanoğlu Mehmetbey University • Aim: Symptom relief
Last updated Aug 07, 2026 00:00 UTC
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Can a simple tape ease carpal tunnel pain?
Symptom relief CompletedThis trial tests whether adding kinesio taping to a standard exercise program helps people with carpal tunnel syndrome more than exercise alone. Carpal tunnel syndrome happens when the median nerve is compressed at the wrist, causing pain, numbness, and weakness. Participants wil…
Phase: NA • Sponsor: Istanbul Gelisim University • Aim: Symptom relief
Last updated Aug 05, 2026 00:00 UTC
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Neck pain relief: which nerve stretch works best?
Symptom relief CompletedThis study tested two types of nerve mobilization exercises—slider and tensioner—in 36 adults with chronic neck pain from cervical radiculopathy. Participants received standard care plus one of the two techniques. The goal was to see which better reduces pain, improves neck movem…
Phase: NA • Sponsor: Cairo University • Aim: Symptom relief
Last updated Jun 27, 2026 12:05 UTC
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Simple nerve stretches may boost carpal tunnel relief
Symptom relief CompletedThis study tested whether adding nerve mobilization exercises to standard ultrasound therapy helps people with mild-to-moderate carpal tunnel syndrome. 86 adults aged 20-55 took part. Researchers measured pain, hand strength, and nerve size before and after three weeks of treatme…
Phase: NA • Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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New ultrasound technique may speed carpal tunnel recovery
Symptom relief CompletedThis study compared two surgical treatments for carpal tunnel syndrome: a newer ultrasound-guided procedure with a small incision and traditional open surgery. Researchers wanted to see if the less invasive method leads to faster symptom relief and better hand function. Two hundr…
Phase: NA • Sponsor: Fundacin Biomedica Galicia Sur • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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New injection study aims to ease wrist pain without surgery
Symptom relief CompletedThis study tested three different injection techniques using a sugar-water solution (5% dextrose) to treat mild to moderate carpal tunnel syndrome. 74 adults received one of the methods, and researchers measured pain, tingling, and hand function over three months. The goal was to…
Phase: NA • Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Tiny incision, big relief? study tests Ultrasound-Guided carpal tunnel release
Symptom relief CompletedThis study compared two types of carpal tunnel release surgery: one using ultrasound guidance with a tiny incision (less than 1 cm) and the traditional mini-open method with a slightly larger cut. Forty-one adults with carpal tunnel syndrome were randomly assigned to one of the t…
Phase: NA • Sponsor: Walter Reed National Military Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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New study uses ultrasound to uncover hidden nerve changes in diabetic patients with carpal tunnel
Knowledge-focused CompletedThis completed observational study looked at 84 people to understand how diabetic polyneuropathy (nerve damage from diabetes) changes the median nerve in patients with carpal tunnel syndrome. Researchers used advanced ultrasound techniques, including shear wave elastography and m…
Sponsor: Ankara Etlik City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Can your cane cause carpal tunnel? new study investigates
Knowledge-focused CompletedThis study looked at 30 adults in rehabilitation who needed a walking aid for the first time. Researchers checked their hand and wrist health before and after using the aid, using questionnaires and nerve tests. The goal was to see if using canes or walkers might lead to carpal t…
Phase: NA • Sponsor: Centre Hospitalier Valida • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Ultrasound reveals how hypermobile wrists change the median nerve
Knowledge-focused CompletedThis study used ultrasound to compare how the median nerve changes shape in different wrist positions (neutral, bent, extended, and tilted) between people with generalized joint hypermobility and healthy individuals. 36 women participated. The goal was to understand if hypermobil…
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC