Median nerve neuropathy
MONDO:0003598Disease involving the median nerve, from its origin at the brachial plexus to its termination in the hand. Clinical features include weakness of wrist and finger flexion, forearm pronation, thenar abduction, and loss of sensation over the lateral palm, first three fingers, and radial half of the ring finger. Common sites of injury include the elbow, where the nerve passes through the two heads of the pronator teres muscle (pronator syndrome) and in the carpal tunnel (carpal tunnel syndrome).
Also known as: median nerve peripheral neuropathy, peripheral neuropathy of median nerve, median nerve palsy
31 clinical trials for this condition and its sub-types.
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Body weight may mask carpal tunnel diagnosis on ultrasound
Diagnosis Not yet recruitingThis study looks at whether a person's body weight affects the accuracy of ultrasound for diagnosing carpal tunnel syndrome. Researchers will measure the median nerve size with ultrasound and compare it to standard nerve tests in 120 adults. The goal is to see if weight 'masks' t…
Sponsor: Kayseri City Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:03 UTC
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New turkish diagnostic tool for carpal tunnel syndrome under study
Diagnosis Not yet recruitingThis study aims to translate and test a diagnostic tool called CTS-6 for Turkish-speaking patients with carpal tunnel syndrome. Researchers will enroll 126 adults, including healthy volunteers, people with symptoms, and those already diagnosed. The goal is to ensure the tool is a…
Sponsor: Istanbul University • Aim: Diagnosis
Last updated Jun 27, 2026 09:06 UTC
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Needle vs. knife: new study tests injection as carpal tunnel alternative
Symptom relief Not yet recruitingThis study compares a minimally invasive ultrasound-guided injection to standard open surgery for carpal tunnel syndrome. 72 adults who have not improved with conservative treatments will be randomly assigned to receive either the injection or surgery. The main goal is to see if …
Phase: NA • Sponsor: Universidade Federal de Pernambuco • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Electric zaps to wrist muscles may speed hand recovery after nerve surgery
Symptom relief Not yet recruitingThis study tests whether adding EMG-triggered electrical stimulation to standard physiotherapy can help people regain hand function after median or ulnar nerve repair. The stimulation activates wrist and finger extensor muscles weakened by post-surgery immobilization. Twenty-six …
Phase: NA • Sponsor: Pamukkale University • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Knife or stretch? trial to settle best fix for trapped arm nerve
Symptom relief Not yet recruitingThis trial compares surgery to physiotherapy for people with persistent median nerve compression in the upper arm. 160 adults will be randomly assigned to either a nerve release operation or guided stretching exercises. The main goal is to see which treatment leads to better symp…
Phase: NA • Sponsor: Tampere University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Night splints for carpal tunnel: which angle works best?
Symptom relief Not yet recruitingThis study compares three different wrist splint positions (flexed, neutral, and extended) worn at night for eight weeks in 108 adults with mild to moderate carpal tunnel syndrome. All participants also receive education and exercises. The goal is to see which position best reduc…
Phase: NA • Sponsor: Istanbul University • Aim: Symptom relief
Last updated Jun 27, 2026 11:01 UTC
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Can magnets ease carpal tunnel pain? new study investigates
Symptom relief Not yet recruitingThis study tests whether low-frequency magnetic field therapy (magnetotherapy) can reduce pain and improve function in people with mild-to-moderate carpal tunnel syndrome. Sixty adults will be randomly assigned to receive either active magnetotherapy, a placebo device, or standar…
Phase: NA • Sponsor: Fatih Sultan Mehmet Training and Research Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Tiny incision, big relief: new ultrasound surgery for elbow nerve pain
Symptom relief Not yet recruitingThis study tests a minimally invasive procedure to release a trapped median nerve at the elbow (lacertus syndrome) using ultrasound guidance. Instead of a large cut, doctors make a tiny incision and cut the tight band pressing on the nerve. The goal is to reduce pain, improve han…
Phase: NA • Sponsor: GCS Ramsay Santé pour l'Enseignement et la Recherche • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Ultrasound peek at carpal tunnel nerves: diabetes link explored
Knowledge-focused Not yet recruitingThis study uses ultrasound to measure the size and blood flow of the median nerve in people with carpal tunnel syndrome. Researchers will compare findings between diabetic and non-diabetic patients to see if diabetes affects nerve changes. The goal is to better understand the con…
Sponsor: SB Istanbul Education and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Mind over nerve? study tests imagery plus stretches for better mobility
Knowledge-focused Not yet recruitingThis pilot study will test whether combining movement imagery techniques (like watching or imagining movements) with nerve stretching exercises can improve how the median nerve responds to pressure and stretch. Ten healthy volunteers will receive both the combined treatment and n…
Phase: NA • Sponsor: University of Gran Rosario • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:09 UTC