Knife or stretch? trial to settle best fix for trapped arm nerve

NCT ID NCT07484100

Not yet recruiting Symptom relief Sponsor: Tampere University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares surgery to physiotherapy for people with persistent median nerve compression in the upper arm. 160 adults will be randomly assigned to either a nerve release operation or guided stretching exercises. The main goal is to see which treatment leads to better symptom relief after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: surgery (proximal median nerve release) and physiotherapy (nerve stretching exercises)
What this could lead to: If surgery proves more effective, it could become a standard treatment for stubborn median nerve compression in the arm.
What could go wrong: This is a small, early-stage trial that hasn't started yet. Surgery carries typical risks like infection or nerve damage, and the results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

median nerve neuropathy nerve compression syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARPAL TUNNEL SURGERY MEDIAN NERVE COMPRESSION MEDIAN NERVE ENTRAPMENT

Contacts and locations

Locations

Seinäjoki Central Hospital

Seinäjoki, Finland
Tampere University Hospital

Tampere, Finland

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