Lichen planus, oral
MONDO:0043923A chronic, autoimmune inflammatory condition of the mucous membranes in the oral cavity that affects approximately two percent of the population and is most often seen in middle aged women. It is characterized by white, lacy patches; red, swollen tissue; papules and plaques; or open sores. The lesions are typically bilateral.
Also known as: oral lichen planus, olp - oral lichen planus
28 clinical trials for this condition and its sub-types.
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New hope for chronic mouth condition: baricitinib trial launches
Disease control OngoingThis study tests whether baricitinib, a drug used for arthritis, can help people with moderate to severe oral lichen planus—a painful mouth condition. Ten adults who haven't improved with other treatments will take the drug for six months. Researchers will measure changes in mout…
Phase: PHASE2 • Sponsor: University of North Carolina, Chapel Hill • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Scientists hunt for clues to why lichen planus treatment fails
Knowledge-focused OngoingThis study follows 110 adults with lichen planus who are using topical steroids, the standard first treatment. Researchers will collect clinical details, saliva, blood, and tissue samples to identify factors linked to poor response. The goal is to understand why some patients don…
Sponsor: University of Aberdeen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC