New hope for chronic mouth condition: baricitinib trial underway

NCT ID NCT06158113

First seen Jan 23, 2026 · Last updated May 16, 2026 · Updated 19 times

Summary

This study tests whether baricitinib, a drug that calms the immune system, can help people with moderate to severe oral lichen planus—a painful, long-lasting mouth condition. Ten adults who have not responded to other treatments will take the drug for six months. Researchers will measure changes in mouth sores and quality of life, and watch for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UNC Dermatology and Skin Cancer Center

    Chapel Hill, North Carolina, 27516, United States

Conditions

Explore the condition pages connected to this study.