Juvenile idiopathic arthritis
MONDO:0011429Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases).
Also known as: Arthritis, Juvenile Rheumatoid, JIA, Juvenile idiopathic arthritis, juvenile idiopathic arthritis, juvenile rheumatoid arthritis, rheumatoid arthritis, systemic juvenile, susceptibility to, acute juvenile rheumatoid arthritis, monarticular juvenile rheumatoid arthritis
137 clinical trials for this condition and its sub-types, 107 tagged with Juvenile idiopathic arthritis itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Juvenile idiopathic arthritis
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Polyarticular juvenile idiopathic arthritis 14 trials · 16 incl. sub-types
Most studied deeper sub-types
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New arthritis drug trial for kids: could filgotinib help?
Disease control Stopped earlyThis study is testing the drug filgotinib in children aged 8 to 17 with juvenile idiopathic arthritis (JIA), a condition causing joint pain and swelling. The goal is to see how the drug moves through the body and if it is safe. Ten children with moderate to severe JIA that is not…
Phase 1 • Sponsor: Alfasigma S.p.A. • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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Can an extra shot boost COVID protection in autoimmune patients?
Disease control Stopped earlyThis study tests whether an additional dose of a COVID-19 vaccine can improve immune protection in adults and children with autoimmune diseases like rheumatoid arthritis, lupus, multiple sclerosis, and others who are taking immunosuppressive medications. Participants who had a we…
Phase 2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Could a tiny ear device ease arthritis pain in kids?
Symptom relief Stopped earlyThis study tested whether a small device that sends mild electrical pulses to the vagus nerve (through the ear) can reduce pain and inflammation in children with juvenile idiopathic arthritis. The trial planned to enroll children ages 5 to 18, but was terminated early after only …
Phase 2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Scientists hunt for clues to tell infection apart from inflammation in Kids' joints
Knowledge-focused Stopped earlyThis study looked for new markers in blood and joint fluid to help doctors tell the difference between septic arthritis (a joint infection) and juvenile idiopathic arthritis (an inflammatory condition) in children. Researchers planned to analyze samples from 100 children under 15…
Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Gut microbiome study in kids with autoimmune diseases ends early
Knowledge-focused Stopped earlyThis study aimed to compare the gut bacteria of children newly diagnosed with juvenile idiopathic arthritis, type 1 diabetes, or inflammatory bowel disease with those of their healthy siblings. Researchers wanted to see if differences in gut microbes and diet could explain why so…
Sponsor: University Hospital, Clermont-Ferrand • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC