Isolated spina bifida

This study tests a new, minimally invasive surgical technique to repair open neural tube defects (spina bifida) in unborn babies. Instead of opening the uterus, surgeons use a tiny camera and tools inserted through small incisions. The goal is to close the spinal defect effective…

This study tested a new surgical procedure for people with Chiari malformation and type II skull base depression, a condition where brain tissue extends into the spinal canal. The surgery combined decompression, joint release, and fusion to relieve pressure and stabilize the spin…

This study tested a mix of treatments—biofeedback, osteopathic care, behavioral training, diet changes, and electrical stimulation—to help children with spina bifida control their bladder. 66 kids aged 10-17 took part, receiving either the combo therapy or standard care for 10 we…

This study tested three different materials (blood clot, platelet-rich fibrin, and concentrated growth factor) combined with two types of rinses to help regrow root tissue in 30 immature permanent teeth with dead nerves. Participants aged 9 to 25 were followed for 12 months using…

This study tested a surgery performed before birth to repair a spinal defect called myelomeningocele, a severe form of spina bifida. The goal was to see if fixing the spine in the womb could reduce brain problems and nerve damage after birth. 38 pregnant women carrying fetuses wi…

This study tested a new, less invasive surgical technique to repair spina bifida before birth. Seven pregnant women carrying babies with the condition underwent a fetoscopic procedure using small incisions and a camera. The goal was to see if the surgery was feasible and safe for…

This study examined spinal fluid from 32 children with tethered spinal cord to see if inflammation plays a role in the condition. Researchers collected fluid samples during surgery and looked for markers of inflammation. The goal was to better understand how the spinal cord gets …

This study looked at 173 infants with myelomeningocele, a severe form of spina bifida, to see if the timing of their surgery (before or after birth) affects their risk for sleep-disordered breathing. Researchers used sleep studies to measure breathing problems and later checked t…

This study looked at 21 pregnant women and their babies to understand how surgery before birth changes the immune system. The goal was to find out if immune system activation might cause early labor. Researchers collected blood samples and studied the placenta to track immune cha…

This study looked at how well children with myelomeningocele (a type of spina bifida) can perform two tasks at the same time, like moving blocks while tapping a rhythm, compared to children without the condition. Researchers tested 60 children aged 7-18 using simple hand and thin…