Fetal vs. postnatal surgery: which leads to better sleep breathing for spina bifida babies?

NCT ID NCT04251806

Completed Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 173 infants with myelomeningocele, a severe form of spina bifida, to see if the timing of their surgery (before or after birth) affects their risk for sleep-disordered breathing. Researchers used sleep studies to measure breathing problems and later checked the children's brain development at age 2. The goal was to understand how surgery timing and sleep breathing relate to long-term development.

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Conditions

The condition(s) this trial relates to.

myelomeningocele sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYELOMENINGOCELE SLEEP DISORDERED BREATHING

Contacts and locations

Locations

Children's Hospital Colorado

Aurora, Colorado, 80045, United States
Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, 19104, United States
Children's Minnesota

Minneapolis, Minnesota, 55404, United States
Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States
Mayo Clinic

Rochester, Minnesota, 55905, United States
Mott Children's Hospital

Ann Arbor, Michigan, 48109, United States
University of Alabama at Birmingham

Birmingham, Alabama, 35294, United States
University of Texas-Houston

Houston, Texas, 77030, United States
Washington University

St Louis, Missouri, 63110, United States

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