Fetal vs. postnatal surgery: which leads to better sleep breathing for spina bifida babies?

NCT ID NCT04251806

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at 173 infants with myelomeningocele, a severe form of spina bifida, to see if the timing of their surgery (before or after birth) affects their risk for sleep-disordered breathing. Researchers used sleep studies to measure breathing problems and later checked the children's brain development at age 2. The goal was to understand how surgery timing and sleep breathing relate to long-term development.

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Conditions

The condition(s) this trial relates to.

myelomeningocele sleep apnea syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Children's Hospital Colorado

    Aurora, Colorado, 80045, United States

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Children's Minnesota

    Minneapolis, Minnesota, 55404, United States

  • Cincinnati Children's Hospital Medical Center

    Cincinnati, Ohio, 45229, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Mott Children's Hospital

    Ann Arbor, Michigan, 48109, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of Texas-Houston

    Houston, Texas, 77030, United States

  • Washington University

    St Louis, Missouri, 63110, United States