Keyhole surgery in the womb could fix spinal defects with fewer risks
NCT ID NCT02230072
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This study tests a new, minimally invasive surgical technique to repair open neural tube defects (spina bifida) in unborn babies. Instead of opening the uterus, surgeons use a tiny camera and tools inserted through small incisions. The goal is to close the spinal defect effectively while lowering risks like uterine rupture and premature birth. Pregnant women carrying a single fetus with a spinal defect between T1 and S1 and signs of Chiari II malformation may be eligible.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- fetoscopy (minimally invasive surgical device)
- What this could lead to
- If successful, this technique could offer a safer way to repair fetal spinal defects, potentially reducing complications like uterine rupture and allowing vaginal delivery.
- What could go wrong
- This is an early-phase trial with only 60 participants, so the procedure may not prove safer or as effective as open surgery. Risks include preterm birth or membrane rupture.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Stanford University: Lucille Packard's Childrens Hospital
Stanford, California, 94305, United States
-
Texas Childrens Hospital
Houston, Texas, 77030, United States