Iris disorder

This phase 3 trial tested whether a yeast-derived immune stimulant (GM-CSF) and a peptide vaccine, alone or together, could prevent melanoma from returning after surgery. 815 patients with no visible cancer after complete surgical removal of advanced melanoma were randomly assign…

This study tests whether a graft made from a patient's own or donor stem cells can repair the cornea's surface in people with limbal stem cell deficiency, a condition that causes pain, scarring, and vision loss. A small biopsy of limbal tissue is taken from a healthy eye or donor…

This study tested a small implant called Supraflow v2.2 in 57 adults with open-angle or narrow-angle glaucoma. The implant is placed inside the eye to help drain fluid and lower eye pressure. The goal was to see if it safely reduces pressure and the need for daily eye drops over …

This early-phase trial tested a new personalized therapy called TBio-4101 for people with advanced melanoma that had stopped responding to standard treatments. The therapy uses a patient's own tumor-fighting immune cells, which are collected, multiplied in the lab, and then infus…

This study tested a new, less invasive surgery called MIMS for people with glaucoma. The goal was to see if it lowers eye pressure as well as traditional surgery but with fewer side effects. 23 adults with glaucoma took part. The results will help doctors understand if MIMS is a …

This study tested whether a thin, clear membrane from the back of the cornea (Descemet's membrane) can help the eye heal in people with limbal stem cell deficiency, a condition that can cause blindness. Nineteen participants received the membrane as a patch on the eye's surface. …

This study tested a new method called metagenomic deep sequencing (MDS) to find the cause of eye infections. 100 adults with suspected infectious uveitis or endophthalmitis were randomly assigned to have their doctors receive MDS results or not, in addition to standard tests. The…

This study tested whether wearing virtual reality glasses during open inguinal hernia surgery with spinal anesthesia could lower anxiety and boost comfort. 84 patients were split into two groups: one watched a video using VR goggles during surgery, the other did not. Researchers …

This study tested two different fluid management approaches during brain tumor removal surgery. 32 adults were monitored to see which method led to better recovery, measured by blood lactate levels. The goal was to find the best way to give fluids during surgery to improve patien…

This study examined whether pseudoexfoliation syndrome (an eye condition) is related to carpal tunnel syndrome (a wrist nerve problem). Researchers measured blood markers in 159 adults aged 50-80. The goal was to see if these conditions share a common cause, not to test a treatme…

This study looked at 30 men taking alpha-blocker drugs for urinary symptoms who were scheduled for cataract surgery. Researchers used a special eye scan to measure the thickness of iris muscles and pupil size. The goal was to see if these measurements could predict intraoperative…