Lab-grown stem cells may restore damaged eye surfaces
NCT ID NCT00845117
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a graft made from a patient's own or donor stem cells can repair the cornea's surface in people with limbal stem cell deficiency, a condition that causes pain, scarring, and vision loss. A small biopsy of limbal tissue is taken from a healthy eye or donor, stem cells are grown into a sheet in the lab, and then transplanted onto the damaged eye. The trial measures improvements in vision, surface healing, and blood vessel growth.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cultivated limbal stem cell graft
What this could lead to
If successful, this approach could restore a clear corneal surface and improve vision in people with limbal stem cell deficiency, potentially reducing the need for corneal transplants.
What could go wrong
This is a small, early-stage study with 21 participants, so results may not apply to everyone. Risks include graft failure, infection, or rejection, and long-term benefits are not yet proven.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University Hospital Antwerp
Antwerp, Edegem, 2650, Belgium