New eye drops aim to repair cornea damage in rare vision disorder
NCT ID NCT06452316
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial is testing an experimental eye drop called CSB-001 in 75 people with limbal stem cell deficiency, a condition where the eye's surface can't heal properly, leading to pain and vision loss. The study will check if the drops are safe and if they help improve signs of the disease. Participants will receive the drops in two separate dosing periods with a break in between, followed by a period of observation only.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CSB-001 ophthalmic solution (a modified human growth factor protein)
What this could lead to
If successful, this could point toward a new treatment option for limbal stem cell deficiency, a condition that can cause vision loss.
What could go wrong
This is a very early Phase 1 trial with only 75 people, focused mainly on safety. It is too soon to know if the drug works, and many early-stage treatments do not pan out.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Francis Price Jr, MD
RECRUITINGIndianapolis, Indiana, 46260, United States
Contact
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Legacy Devers Eye Institute
RECRUITINGPortland, Oregon, 97210, United States
Contact
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Loma Linda University Eye Institute
RECRUITINGLoma Linda, California, 92354, United States
Contact
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Midwest Cornea Associates, LLC
RECRUITINGCarmel, Indiana, 46290, United States
Contact
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Minnesota Eye Consultants
RECRUITINGMinnetonka, Minnesota, 55305, United States
Contact
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Stuart A. Terry, MD PA
RECRUITINGSan Antonio, Texas, 78212, United States
Contact