Intestinal obstruction

This completed phase 2 trial tested whether the drug cediranib, given with chemotherapy, is safe for women with advanced ovarian cancer who are at risk of bowel obstruction. 30 participants received the combination. The study focused on whether the treatment caused serious bowel …

This study tested a special collagen mesh (Surgicoll-Mesh) placed in the abdomen during surgery for cancers that have spread to the lining of the belly. The goal was to see if it could prevent serious problems like bowel blockages, infections, or the need for more surgery. 60 adu…

This study looked at 52 children who needed their colostomy reversed. Half had the stoma closed with full-thickness stitches, the other half with single-layer extramucosal stitches. The goal was to see which method caused fewer leaks or narrowing in the first month after surgery.

This study compares two surgeries—One Anastomosis Gastric Bypass and Duodenojejunostomy—for treating Superior Mesenteric Artery Syndrome (SMAS), a rare condition where the duodenum is compressed, causing severe nausea, vomiting, and weight loss. Twenty participants were randomly …

This study tested whether a bedside ultrasound (POCUS) can accurately detect or rule out bowel obstruction in 150 adults with abdominal pain. Doctors performed the ultrasound after a physical exam, then compared results to a CT scan. The goal is to see if this quick, radiation-fr…

Researchers are studying whether a stoma self-care app, accessed through the LINE messaging platform, can help people with an enterostomy improve their self-care and quality of life. The study enrolls 50 adults who have a colostomy and can use a smartphone. It combines two models…

This pilot study compares two types of surgical mesh, biological and synthetic, used during a combined operation for pelvic organ prolapse and rectal prolapse. Thirty participants with obstructed defecation syndrome and pelvic organ prolapse undergo laparoscopic mesh sacropexy pl…

This trial investigates whether laser acupuncture, a non-invasive therapy that uses low-intensity light on traditional acupoints, can help people with adhesive small bowel obstruction—a common complication after abdominal surgery where scar tissue blocks the intestine. The study …

This study tested whether putting special elastic tape on the belly can help relieve severe pain, bloating, and nausea in people with advanced cancer who have bowel blockage and fluid buildup. 38 adults whose symptoms didn't improve after standard treatments were randomly assigne…

This study tested whether a structured recovery plan (ERAS) could reduce infections and speed up recovery compared to standard care in 102 adults who had emergency abdominal surgery for a blocked or perforated bowel. Participants were randomly assigned to receive either the ERAS …

This study tested a 12-week nursing program based on the Roy Adaptation Model for adults who recently had a colostomy. It aimed to reduce anxiety and depression and improve quality of life compared to standard care. 115 participants were randomly assigned to either the special pr…

This study tested whether adding interactive videos to standard care improves quality of life and recovery in patients with early postoperative bowel obstruction. 462 adults who had abdominal surgery were randomly assigned to either standard care alone or standard care plus a ser…

This study tested whether aromatherapy (breathing lavender oil) or acupressure (gentle thumb pressure on specific points) could reduce pain and improve sleep in 100 children aged 6-12 after abdominal surgeries like appendix or hernia repair. The goal was to find simple, non-drug …

This study compares how often bowel obstruction occurs after two types of appendix removal surgery: open appendectomy and laparoscopic appendectomy. Fifty people with acute appendicitis will be randomly assigned to one of the two procedures. The goal is to see whether the minimal…

This study looked at how emergency general surgery affects pregnant women and their unborn babies. Researchers planned to follow pregnant women who needed surgery for problems like appendicitis or gallbladder disease. The goal was to learn more about the safety of these surgeries…

This study reviewed the medical records of 504 adults hospitalized with small bowel obstruction to see how using a water-soluble contrast study affected their care. The goal was to find ways to improve patient safety, shorten hospital stays, and reduce complications. Because it i…

This study looked at 90 emergency surgery patients who needed their intestine reconnected. Half had a stapled connection and half had a hand-sewn one. Researchers tracked complications like leaks, infections, bleeding, pain, and hospital stay to see which method worked better.

This study tested whether the Capillary Leak Index (CLI), a score based on routine blood tests, can predict which patients are at higher risk of dying after developing a serious abdominal infection following surgery. Researchers followed 100 critically ill adults in the ICU for 2…

This study looked at the records of 2500 adults admitted to the hospital with serious belly problems like blockages or infections. The goal was to compare outcomes for different treatments, including surgery, keyhole surgery, radiology procedures, and comfort care. By grouping pa…

This completed observational study collected over 3,700 PillCam SB3 capsule endoscopy videos from standard care procedures. The goal was to build a large database of images showing both normal and diseased small intestine tissue. Researchers will use this data to develop and vali…

This study looked at 312 patients who had a small bowel obstruction but had never undergone abdominal surgery. Researchers wanted to find out what caused the blockage and how patients fared over the next five years. By reviewing medical records, they hope to guide better treatmen…