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Intestinal fistula
MONDO:1040017An intestinal disorder characterized by an opening in the intestine to some epithelial surface.
55 clinical trials for this condition and its sub-types.
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Broader categories
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Surgical glue may boost healing for tough anal fistulas
Disease control OngoingThis study compares a standard seton (a thread used to drain and heal fistulas) with one coated in Glubran, a surgical glue with antimicrobial and healing properties. The trial includes adults with high or complex anal fistulas, a painful condition that can cause infection and in…
Phase: NA • Sponsor: Kasr El Aini Hospital • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Could your own blood heal a painful fistula? new trial investigates
Disease control OngoingThis study tests whether a gel made from a patient's own blood (platelet-rich plasma) can help close perianal fistulas—abnormal tunnels that form near the anus. One hundred adults with this condition will receive the gel during a procedure, and doctors will check if the fistula h…
Phase: NA • Sponsor: Uşak University • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Stem cell shot for Crohn's fistulas: hope or hype?
Disease control TerminatedThis study aimed to test whether injecting donor stem cells directly into fistulas could safely help heal them in people with Crohn's disease who have an ileal pouch. The trial was withdrawn before any participants were enrolled, so no results are available. The approach was expe…
Phase: PHASE1 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Growth factor plug aims to heal stubborn anal fistulas
Disease control OngoingThis study tests whether a collagen plug soaked with a lab-made growth factor (rhPDGF-BB) can safely help heal complex anal fistulas—abnormal tunnels between the rectum and skin. The plug is implanted during a procedure, and the growth factor is meant to boost tissue repair. The …
Phase: PHASE2 • Sponsor: Alexander Hawkins • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Could your own fat cells heal Crohn's fistulas? new trial tests it
Disease control OngoingThis Phase 3 trial tests whether injecting a patient's own fat-derived stem cells, along with a glue, can close fistulas caused by Crohn's disease. 46 adults with Crohn's and at least one fistula are taking part. The main goal is to see if the fistula closes completely.
Phase: PHASE3 • Sponsor: Anterogen Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Fish skin patch may seal anal fistulas in small mayo trial
Disease control ENROLLING_BY_INVITATIONThis study tests whether a fish skin device called Kerecis SurgiClose can help heal anal fistulas and related wounds that won't close on their own. Twenty adults with cryptoglandular fistulas will receive the fish skin patch during a procedure. Doctors will check if the fistula i…
Phase: NA • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 26, 2026 19:12 UTC
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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600 patients followed to see how anal fistula surgery affects recovery and continence
Knowledge-focused OngoingThis study follows 600 adults who had surgery for anal fistula, a painful infected tunnel near the anus. Researchers want to see how many are fully healed after 2 years and whether the surgery causes any loss of bowel control. The goal is to learn which surgical methods work best…
Sponsor: Groupe Hospitalier Diaconesses Croix Saint-Simon • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC