Could your own blood heal a painful fistula? new trial investigates

NCT ID NCT04187651

Ongoing Disease control Sponsor: Uşak University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a gel made from a patient's own blood (platelet-rich plasma) can help close perianal fistulas—abnormal tunnels that form near the anus. One hundred adults with this condition will receive the gel during a procedure, and doctors will check if the fistula has healed using exams and MRI scans. The goal is to see if this natural approach works better than standard surgical methods.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich plasma (PRP) gel made from the patient's own blood
What this could lead to: If it works, this could offer a less invasive, natural treatment option for perianal fistula that may improve healing and reduce recurrence.
What could go wrong: This is an early-stage study without a control group, so results may not prove effectiveness. PRP is generally safe, but the fistula may still return or not heal completely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anal fistula

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FISTULA-IN-ANO

Contacts and locations

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Locations

Uşak University

Uşak, 64100, Turkey (Türkiye)

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