Intestinal fistula

This study compared two ways of feeding patients who developed a leak (fistula) after upper gastrointestinal surgery: feeding through a tube into the gut (enteral nutrition) versus feeding through a vein (parenteral nutrition). The goal was to see if enteral nutrition could help …

This early-stage study tested whether injecting donor stem cells directly into fistulas (abnormal tunnels) could help people with Crohn's disease. The trial planned to enroll 25 adults but was terminated early. The goal was to check safety and see if the treatment could lead to c…

This study tested the long-term safety and effectiveness of a stem cell treatment called darvadstrocel (Alofisel) for people with Crohn's disease and complex anal fistulas. Researchers planned to give one injection of the stem cells and follow 53 participants over several visits,…

This study tested a treatment called darvadstrocel for children with Crohn's disease who have complex perianal fistulas (abnormal tunnels near the anus). Seven participants received an injection of the treatment near the fistula after a cleaning procedure. The goal was to see if …

This study compared two types of drainage setons—Ethibond suture and vessel loop—for treating complex anal fistulas. The goal was to see which material drains infection better, lasts longer, and improves quality of life. However, the trial was terminated early after enrolling onl…