Could your own fat cells heal Crohn's fistulas? new trial tests it

NCT ID NCT04612465

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 3 trial tests whether injecting a patient's own fat-derived stem cells, along with a glue, can close fistulas caused by Crohn's disease. 46 adults with Crohn's and at least one fistula are taking part. The main goal is to see if the fistula closes completely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Autologous adipose-derived stem cells (a patient's own fat stem cells) combined with fibrin glue

What this could lead to

If it works, this could offer a new way to close hard-to-treat fistulas in Crohn's disease, potentially reducing the need for surgery or long-term medication.

What could go wrong

This is a small Phase 3 trial with only 46 people, so results may not apply to everyone. Stem cell treatments can have side effects like infection or inflammation, and the fistula might not fully close.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal fistula Crohn disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Asan Medical Center

    Seoul, Seoul, 05505, South Korea

  • Samsung Medical Center

    Seoul, Seoul, 06351, South Korea

  • Seoul Natinoal Univetsity Hospital

    Seoul, Seoul, 03080, South Korea

  • Severance

    Seoul, Seodaemun-gu, 03722, South Korea