Iatrogenic disease

This study follows 73 people who received a shoulder replacement using the Anatomical Shoulder Domelock System. The goal is to see how well the device works and how safe it is over 10 years. Participants have conditions like arthritis or avascular necrosis and have not improved w…

This study will follow 5,000 adults who have had endoscopic procedures for weight loss, such as stomach stapling through a scope or gastric balloons. Researchers will track weight, blood pressure, diabetes, and cholesterol for up to 10 years to see how well these procedures work …

This study tests a new way to manage medications for older adults who take many drugs. The goal is to reduce harmful side effects by improving how doctors, pharmacists, and hospitals work together. About 1,500 elderly patients in France will take part.

This study tests whether using special disinfectant caps on central venous catheters can lower the rate of bloodstream infections in intensive care patients. About 120 adults in a neurological ICU will be monitored. The caps are pre-treated with alcohol and are meant to block ger…

This study tests whether garlic tablets can prevent infections that patients often get while in the intensive care unit (ICU). Researchers will give garlic tablets to some ICU patients and compare them to others who do not receive the tablets. The goal is to see if garlic lowers …

This study follows 200 adults on ECMO (a heart-lung machine) for severe breathing problems. Researchers track how many get hospital-acquired infections and measure antibiotic levels in their blood and lungs. The goal is to learn more about infections and drug dosing in these crit…

This study looks at how the bacteria and fungi living in and on our bodies change when someone stays in the hospital. Researchers will take swabs and samples from 250 patients aged 2 and older during their hospital stay and follow-up visits. The goal is to learn which germs sprea…

This study looks at whether hospitals can safely reduce the use of fall prevention alarms. About 300 hospital staff and units will try different strategies like education and feedback to see if they can lower alarm use without increasing patient falls. The goal is to improve pati…

This study tests a computer tool that uses maps and location data to help infection preventionists find and stop hospital-acquired infections faster. About 25 infection prevention staff will use the tool and report how easy it is to use and whether it helps them respond more quic…

This study looks at whether teaching hand hygiene with cognitive behavioral therapy (a method that changes thinking patterns) can improve healthcare workers' awareness of hospital infections. About 140 healthcare workers will take part. The goal is to see if this approach makes t…

This study tests whether using rapid, advanced lab tests to identify the exact bacteria causing a severe infection can help doctors choose the right antibiotics faster. About 190 adults with sepsis in Greek ICUs will either get standard care or the new testing strategy. The goal …

This study tests whether a rapid PCR test can help doctors choose the right antibiotics within 24 hours for immunocompromised ICU patients with pneumonia. Standard lab tests take days, which can lead to incorrect or overly broad antibiotics. The trial involves 31 adults with weak…

This study looks back at 351 patients who had epidural catheters or ports placed for pain management over 23 years. Researchers want to find out how often infections happen and what factors, like how long the device stays in or where it's placed, increase the risk. The goal is to…