Hypermobility spectrum disorder
MONDO:1040027An array of connective tissue disorders characterized by joint instability and chronic pain. Fatigue and other systemic symptoms that affect daily function may occur as well. These diseases are scored using the Beighton scoring system and one of more secondary musculoskeletal manifestations including post-traumatic symptoms, pain, altered proprioception, and a variety of other characteristics like pes planus, kyphosis, scoliosis, or joint misalignment.
Also known as: BJHS, benign joint hypermobility syndrome, joint hypermobility syndrome
16 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Could online pilates ease pain for those with stretchy joints?
Symptom relief CompletedThis study investigates whether an online Pilates program designed for people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder can reduce pain and improve function. Participants follow 25-minute guided videos three times a week for eight weeks. Researche…
Phase: NA • Sponsor: Clarkson University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Ear stimulation device shows promise for Ehlers-Danlos relief
Symptom relief CompletedThis study tested whether a small, at-home device that stimulates a nerve in the ear can improve symptoms like pain, fatigue, sleep, and mood in people with hypermobile Ehlers-Danlos syndrome (hEDS). Twenty-five adults with hEDS used the device daily for two weeks, with some rece…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Could a simple ear device ease hEDS symptoms?
Symptom relief CompletedThis study tested a wearable device that delivers mild electrical stimulation to the ear in 30 adults with hypermobile Ehlers-Danlos syndrome (hEDS). The goal was to see if it could improve quality of life by reducing symptoms like pain, fatigue, sleep problems, and anxiety. Part…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Can flexible joints and flat feet worsen scoliosis? new study investigates
Knowledge-focused CompletedThis completed study examined 22 adolescents with idiopathic scoliosis to see if joint hypermobility (flexibility) and foot posture are linked to the severity of their spinal curve. Researchers measured hypermobility with the Beighton Score, foot posture with the Foot Posture Ind…
Sponsor: Istinye University • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Could bendy joints be a clue in ADHD?
Knowledge-focused CompletedThis study looks at whether children with ADHD are more likely to have very flexible joints (benign joint hypermobility) and if a certain blood marker differs. Researchers will compare 171 children aged 6 to 12—some with ADHD and some without—using physical exams and blood tests.…
Sponsor: Antalya Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Baby sleep study: does loose joints mean less rest?
Knowledge-focused CompletedThis study looked at whether infants aged 6 to 9 months with joint hypermobility (very flexible joints) have different sleep patterns than other babies. Researchers used a parent questionnaire to compare sleep duration, night wakings, and sleep problems between 60 infants with an…
Sponsor: Nigde Omer Halisdemir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Could your finger length reveal why You're Double-Jointed?
Knowledge-focused CompletedThis study examined 180 young adults to see if the ratio of their index to ring finger length (2D:4D) is linked to joint hypermobility (being double-jointed). The idea is that this finger ratio may reflect hormone levels before birth. Researchers measured joint flexibility using …
Sponsor: Nigde Omer Halisdemir University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Ultrasound reveals how hypermobile wrists change the median nerve
Knowledge-focused CompletedThis study used ultrasound to compare how the median nerve changes shape in different wrist positions (neutral, bent, extended, and tilted) between people with generalized joint hypermobility and healthy individuals. 36 women participated. The goal was to understand if hypermobil…
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC