Hemorrhagic stroke

This study aimed to see if sodium lactate could improve blood flow in the brain after a severe type of stroke called subarachnoid hemorrhage. Only 3 patients were enrolled before the study was stopped early. The goal was to measure changes in brain blood flow using a special scan…

This study looked at whether adding the drug pioglitazone to a keyhole brain surgery (MIPS) could help people recover from a severe bleeding stroke. Only one person took part before the study was stopped early. The goal was to see if the combination was safe and helped clear the …

This study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…

This study tested a drug called edaravone dexborneol (Sanbexin IV) in 80 people who had a brain bleed (intracerebral hemorrhage). The goal was to see if it is safe and helps recovery when added to standard care. The trial was stopped early, so the results are limited and more res…

This study looked at a device called the Pipeline Flex Embolization Device with Shield Technology to treat ruptured brain aneurysms that are hard to fix with surgery or coils. The goal was to see if it could safely block the aneurysm and prevent rebleeding. The study was stopped …

This study aimed to see if the antibiotic minocycline could improve outcomes after a stroke. Participants were to receive either standard care plus minocycline pills for five days, or standard care alone. However, the trial was stopped early after enrolling only 2 people, so no m…

This study tested a device called CoolStat that is placed in the nose to cool down brain-injured patients with fever in the ICU. The goal was to see if it could safely and quickly bring their temperature to normal. Only 9 patients were enrolled before the study was stopped early,…

This study compared two breathing techniques (CPAP and eSigh) in 18 patients with brain injury and acute respiratory distress syndrome (ARDS). The goal was to see which method better maintains oxygen levels in the brain without causing harm. The trial was terminated early, so fin…

This study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…

This study tested a software platform called ICU Cockpit that collects and displays vital signs and other data from brain-injury patients in the intensive care unit. The goal was to help doctors make faster, better decisions and to predict complications like strokes or unstable c…

This study looked at whether electrical stimulation of the spinal cord could help widen narrowed brain arteries after a type of stroke called subarachnoid hemorrhage. Only one person was enrolled before the study was stopped early. The goal was to measure changes in blood flow, b…

This pilot study aimed to see if antiseizure drugs like phenobarbital and levetiracetam change brain connectivity patterns in people with severe acute brain injury and reduced consciousness. Only 5 participants were enrolled before the study was terminated. Researchers used resti…

This study aimed to compare two common sedatives, propofol and midazolam, in patients with traumatic brain injury who needed a breathing tube. Researchers wanted to see if one drug led to better recovery or different levels of inflammation markers called cytokines. However, the t…