Sedative showdown in TBI: propofol vs midazolam study halted after just one patient

NCT ID NCT01712477

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study aimed to compare two common sedatives, propofol and midazolam, in patients with traumatic brain injury who needed a breathing tube. Researchers wanted to see if one drug led to better recovery or different levels of inflammation markers called cytokines. However, the trial was terminated early after enrolling only one person, so no meaningful conclusions could be drawn.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
propofol and midazolam

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sparrow Health System

    Lansing, Michigan, 48912, United States

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