Sedative showdown in TBI: propofol vs midazolam study halted after just one patient
NCT ID NCT01712477
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study aimed to compare two common sedatives, propofol and midazolam, in patients with traumatic brain injury who needed a breathing tube. Researchers wanted to see if one drug led to better recovery or different levels of inflammation markers called cytokines. However, the trial was terminated early after enrolling only one person, so no meaningful conclusions could be drawn.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
propofol and midazolam
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Sparrow Health System
Lansing, Michigan, 48912, United States