Cooling the brain through the nose: new device tested for ICU fever
NCT ID NCT06038513
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a device called CoolStat that is placed in the nose to cool down brain-injured patients with fever in the ICU. The goal was to see if it could safely and quickly bring their temperature to normal. Only 9 patients were enrolled before the study was stopped early, so we have very limited information on how well it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
transnasal thermal regulating device (CoolStat)
What this could lead to
If it works, this device could offer a new way to quickly lower fever in ICU patients with brain injuries, potentially reducing complications.
What could go wrong
The trial was terminated early with only 9 participants, so results are very limited. The device may cause shivering or not work better than standard cooling methods.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Maryland Medical Center
Baltimore, Maryland, 21201, United States