Cooling the brain through the nose: new device tested for ICU fever
NCT ID NCT06038513
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a device called CoolStat that is placed in the nose to cool down brain-injured patients with fever in the ICU. The goal was to see if it could safely and quickly bring their temperature to normal. Only 9 patients were enrolled before the study was stopped early, so we have very limited information on how well it works.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- transnasal thermal regulating device (CoolStat)
- What this could lead to
- If it works, this device could offer a new way to quickly lower fever in ICU patients with brain injuries, potentially reducing complications.
- What could go wrong
- The trial was terminated early with only 9 participants, so results are very limited. The device may cause shivering or not work better than standard cooling methods.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Maryland Medical Center
Baltimore, Maryland, 21201, United States
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