Erectile dysfunction
MONDO:0005362Persistent or recurrent inability to achieve or to maintain an erection during sexual activity.
Also known as: erectile dysfunction, erectile dysfunction (disease), male erectile Disorder, sexual impotence (finding), dysfunction, erectile, impotence, impotence, male, impotence, male sexual
100 clinical trials for this condition and its sub-types.
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Broader categories
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New registry to monitor penile implant success in 450 men
Disease control ENROLLING_BY_INVITATIONThis study is a registry that collects real-world information on the safety and effectiveness of Boston Scientific penile implants for erectile dysfunction. It will enroll 450 men who are already scheduled to receive the implant. Researchers will track changes in erectile functio…
Sponsor: Boston Scientific Corporation • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Could stem cells restore erectile function? new trial tests the idea
Disease control OngoingThis study tests whether stem cells from a patient's own bone marrow or fat can improve erectile dysfunction better than platelet-rich plasma or standard treatments. One hundred men with organic ED who did not respond to pills will receive one of these therapies. The goal is to s…
Phase: PHASE2 • Sponsor: National Scientific Medical Center, Kazakhstan • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Can a few extra pills prevent implant infections?
Disease control OngoingThis study looks at whether taking oral antibiotics for 6 extra days after getting a penile implant can lower the chance of infection. Researchers are following 800 men for one year after surgery. The goal is to see if this simple step reduces the need for another surgery to remo…
Phase: EARLY_PHASE1 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Could a single rinse replace antibiotic cocktails in penile implant surgery?
Disease control OngoingThis study compares two methods to prevent infections during first-time penile implant surgery for erectile dysfunction. One group receives the standard antibiotic rinse, the other uses Irrisept, a simpler cleaning solution. Researchers will follow 200 men for one year after surg…
Phase: PHASE3 • Sponsor: Rush University Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Could a blood injection treat erectile dysfunction? new trial investigates
Disease control ENROLLING_BY_INVITATIONThis study compares platelet-rich plasma (PRP) injections to the standard drug alprostadil (Caverject) for treating moderate to severe erectile dysfunction. Sixty men will receive both treatments in a crossover design, with each treatment given as six weekly injections. The main …
Phase: NA • Sponsor: Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Liquid vs tablet: which sildenafil form do men prefer?
Symptom relief OngoingThis study looks at whether men with mild-to-moderate erectile dysfunction are more satisfied with sildenafil in a liquid suspension form compared to tablets that dissolve in the mouth. Researchers will review records of men who took each form for three months. The goal is to see…
Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico • Aim: Symptom relief
Last updated Jul 04, 2026 00:00 UTC
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Nerve-Sparing radiation may help men keep sexual function after prostate cancer treatment
Symptom relief OngoingThis phase 2 trial is testing whether a special type of radiation therapy (SAbR) that avoids the nerves involved in erections can help preserve sexual function in men with localized prostate cancer. About 124 men will be randomly assigned to receive standard SAbR or a version tha…
Phase: PHASE2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 13:03 UTC
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New combo therapy aims to boost erections without drugs
Symptom relief OngoingThis study tests whether combining platelet-rich plasma (PRP) injections with shock wave therapy can improve erections in men with moderate erectile dysfunction. 116 men will receive either the real treatment or a placebo over 9 weeks, then be followed for 6 months. The goal is t…
Phase: NA • Sponsor: Elexial Research Limited • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Could a tiny nerve zap restore erectile function?
Symptom relief OngoingThis study tests whether low-dose electrical stimulation of the pudendal nerve can improve erectile function in men with mild to moderate erectile dysfunction. Twenty-four men will receive a 20-minute stimulation session, and researchers will measure changes in erection hardness,…
Phase: NA • Sponsor: Camilo Jose Cela University • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Could a simple nerve zap treat erectile dysfunction?
Symptom relief OngoingThis study tests whether stimulating the pudendal nerve with a small electrical current can improve erections in men with erectile dysfunction. 72 men aged 18-60 will receive either real stimulation or a sham procedure. Researchers will measure changes in erectile function, hardn…
Phase: NA • Sponsor: Camilo Jose Cela University • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Large registry launched to measure penile implant success
Knowledge-focused OngoingThis study is a registry that collects information from over 1000 men who have surgery to get a penile implant for erectile dysfunction. The main goal is to measure how satisfied patients and their partners are after the procedure. The study does not test a new treatment, but rat…
Sponsor: European Association of Urology Research Foundation • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Blood marker may reveal who benefits from ED drug
Knowledge-focused OngoingThis study looks at whether a blood test measuring the 'atherogenic index' can predict how well the drug tadalafil works for men with erectile dysfunction caused by blood vessel problems. Researchers will give 132 men tadalafil daily for one month and compare their symptom scores…
Sponsor: Taksim Egitim ve Arastirma Hastanesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Depression's hidden toll on male sexual function revealed
Knowledge-focused OngoingThis study looks at how the severity of depression relates to erectile dysfunction and premature ejaculation in 100 married men aged 25–60 in the Sohag region of Egypt. Participants are clinically diagnosed with depression and sexually active. Researchers will use standard questi…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Holistic education study for stress withdrawn before starting
Knowledge-focused TerminatedThis study was designed to test a holistic education program for stress management in people from colonized English-speaking countries. It aimed to help with conditions like stress, PTSD, anxiety, and fatigue using pastoral counseling and self-care activities. However, the study …
Phase: NA • Sponsor: Goddess Zena I. Jones • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Scientists investigate link between blood fats and sickle cell crises
Knowledge-focused OngoingThis study looks at how different types of fats in the blood (like cholesterol) are linked to complications in adults with sickle cell disease. Researchers will follow 116 participants from the French Caribbean islands to track their fat levels over time and during acute events l…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de la Guadeloupe • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC