AI-Crafted supplement aims to restore testosterone naturally

NCT ID NCT07761546

ENROLLING_BY_INVITATION Disease control Sponsor: Varol TUNALI Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a daily nutritional supplement, designed with artificial intelligence to target gut bacteria, can increase testosterone production in men aged 30-65 with functional secondary hypogonadism—a condition where the body doesn't make enough testosterone despite normal testicular function. Half the participants will take the active supplement and half a placebo for 12 weeks, with follow-up for another 12 weeks. The main goal is to see if the supplement raises morning testosterone levels more than placebo, and it will also track symptoms, sexual function, and gut microbiome changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
A fixed-formula, microbiome-targeted oral nutritional supplement (one sachet and one capsule daily for 12 weeks)
What this could lead to
If effective, this supplement could offer a non-hormonal, food-based option to help men with low testosterone raise their levels naturally.
What could go wrong
This is an early proof-of-concept study, so the supplement may not meaningfully raise testosterone. It is not meant to replace standard diagnosis or treatment, and effects may not last after stopping.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Aydın Adnan Menderes University

    Aydin, Turkey (Türkiye)

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