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Dysautonomia
MONDO:0044872An acute or chronic disorder, affecting the sympathetic or parasympathetic nervous system. It can be primary, the result of central nervous system degeneration, or secondary due to diabetes or alcoholism. Patients with the chronic form of this disorder usually have a progressive clinical course and a poor prognosis.
Also known as: dysautonomia
59 clinical trials for this condition and its sub-types.
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Broader categories
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New study tackles long COVID's hidden heart and nerve symptoms
Disease control CompletedThis study tested different treatments for autonomic dysfunction, including POTS, in 381 adults with Long COVID. It compared non-drug approaches and medications to see which best eased symptoms like rapid heart rate and dizziness. The goal was to find effective ways to manage the…
Phase: PHASE2 • Sponsor: Kanecia Obie Zimmerman • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Fingertip wrinkle test may spot nerve damage
Diagnosis CompletedThis study looked at whether a 15-minute hand soak in warm water can help diagnose small fiber neuropathy, a condition that causes pain, numbness, and problems with automatic body functions. Researchers tested 38 adults and compared the wrinkling pattern of their fingertips to st…
Sponsor: HOSPITAL BRITANICO DE BUENOS AIRES • Aim: Diagnosis
Last updated Jun 27, 2026 08:02 UTC
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Walking program shows promise for liver patients
Symptom relief CompletedThis study looked at whether a 16-week brisk walking program, combined with dietary advice, could improve heart rate control and blood vessel health in adults with early-stage cirrhosis (liver scarring). Fifty participants aged 45-75 who were not very active took part. The goal w…
Phase: NA • Sponsor: King Chulalongkorn Memorial Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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Could a gentle zap to the neck help teens with POTS?
Symptom relief CompletedThis study tested a device that gently stimulates a nerve in the neck (called nVNS) to see if it can reduce symptoms like dizziness and fatigue in teenagers with POTS, a condition that causes a rapid heart rate upon standing. Forty teens with newly diagnosed POTS took part at May…
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Ear-Zapping device shows promise for lupus fatigue
Symptom relief CompletedThis study tested a non-invasive device that stimulates the vagus nerve through the ear to see if it can reduce fatigue in people with lupus. 75 participants received either active or sham stimulation over two phases. The main goal was to measure changes in fatigue using a standa…
Phase: NA • Sponsor: Rigshospitalet, Denmark • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Brainwave device may ease stress for healthcare workers
Symptom relief CompletedThis study tested a device called Cereset Research that plays tones in response to a person's brainwaves, aiming to reduce stress and improve sleep. 94 stressed healthcare workers used the device for several sessions and were followed for a year. The goal was to see if the device…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 26, 2026 13:32 UTC
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Nerve test may predict lymphedema therapy success
Knowledge-focused CompletedThis study looked at whether nerve signals (called sympathetic skin response) are linked to how well women respond to standard lymphedema therapy after breast cancer surgery. Thirty women with lymphedema and thirty healthy women had nerve tests and filled out symptom questionnair…
Sponsor: Gaziler Physical Medicine and Rehabilitation Education and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Brain zap tunes heart and gut: new hope for depression?
Knowledge-focused CompletedThis completed study tested whether noninvasive brain stimulation can be personalized by measuring heart rate responses. Researchers mapped the scalp to find the best spot for stimulation in 34 healthy participants and people with depression, anxiety, and gut issues. They compare…
Phase: NA • Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Fibromyalgia's hidden impact on eye blood flow revealed?
Knowledge-focused CompletedThis completed study examined whether fibromyalgia, a condition causing widespread pain, is linked to changes in eye blood vessels. Researchers compared 80 people with and without fibromyalgia using eye scans and symptom questionnaires. The goal was to see if nerve system problem…
Sponsor: Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC
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Fibromyalgia linked to hidden heart changes, new study suggests
Knowledge-focused CompletedThis study looked at whether people with fibromyalgia have early, hidden changes in heart function. Researchers used a special ultrasound technique called Global Longitudinal Strain (GLS) to measure heart muscle movement in 59 fibromyalgia patients and 59 healthy volunteers. The …
Sponsor: Ankara Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Prostate cancer Therapy's hidden heart risk: new study investigates
Knowledge-focused CompletedThis study looked at 10 men to understand why androgen deprivation therapy (ADT) for prostate cancer can lead to high blood pressure. Researchers checked if problems with the nervous system or kidneys were to blame. The goal is to find ways to prevent heart disease in prostate ca…
Phase: PHASE4 • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Can a vein viewer detect nerve damage? new study explores simple diagnostic tool
Knowledge-focused CompletedThis study tested whether the ACCUVEIN, a device that projects veins onto the skin, can detect changes in vein size caused by the nervous system. Researchers had 12 healthy adults lie on a tilt table and slowly move from lying flat to standing upright. They used the device to see…
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC