Developmental dysplasia of the hip

This study compares the standard Pavlik harness treatment to simply monitoring with ultrasound scans for babies with mild hip dysplasia (Graf type 2b and 2c). About 70 babies will be randomly assigned to either wear the harness or be watched closely. The goal is to see if these m…

This early study is testing a new device called the ReNew Hip Implant in 15 people aged 14 to 64 with hip cartilage damage from conditions like osteoarthritis or hip impingement. The implant is surgically placed to repair the cartilage. Researchers are checking if it is safe and …

This study is testing a new hip replacement system called Emphasys Hip Solutions in 30 people with hip osteoarthritis. Researchers will use special X-ray imaging to see how well the implant stays in place over two years. The goal is to make sure the implant is stable and works we…

This study looks at whether simply monitoring babies with mild hip dysplasia is as good as using a brace. The brace, called a Pavlik harness, keeps the hips in proper position but can be hard on families. The trial will follow 514 infants under 3 months old across seven countries…

This study tests a new 3D-printed implant for adults with hip dysplasia, a condition where the hip socket doesn't fully cover the thigh bone, causing pain and gait problems. Ten participants aged 18-45 will receive the implant to see if it is safe and helps improve hip function a…

This study is tracking 550 adults aged 18–75 who receive the Medacta SMS femoral stem during total hip replacement. Researchers will monitor how long the implant lasts, how well the hip functions, patient satisfaction, and quality of life. The goal is to confirm the device's safe…

This study follows 150 people aged 18 to 65 who receive the ROMAX hip resurfacing system to treat hip arthritis or dysplasia. Researchers will track how long the implant lasts and how well the hip functions over 10 years. The goal is to monitor the device's safety and performance…

This study compares two surgical approaches for hip dysplasia: the standard periacetabular osteotomy (PAO) alone versus PAO combined with hip arthroscopy. Researchers will enroll 106 people aged 15-55 with mild or no arthritis. The goal is to see if adding arthroscopy leads to be…

This study tests whether a special ultrasound with contrast dye can show blood flow to the hip joint in real time during surgery for hip dysplasia in infants. About 125 infants aged 4 to 24 months will receive the ultrasound during their hip reduction surgery. The goal is to see …

This study tests whether an artificial intelligence (AI) system can help doctors accurately screen babies for developmental dysplasia of the hip (DDH) using a small, handheld ultrasound device. About 240 babies already scheduled for a standard hip ultrasound will also receive an …

This study looks at whether doing breathing exercises before orthopedic surgery (like knee, hip, or fracture repair) can help your lungs work better after the operation. It involves 36 adults who have used tobacco and are at risk for breathing problems after surgery. Participants…

This study tests whether a program of exercise and patient education can reduce hip and groin pain in people with hip dysplasia, compared to usual care. About 200 adults with confirmed hip dysplasia and at least three months of pain will take part. The main goal is to measure pai…

This study tests whether taking placebo pills alongside standard opioid painkillers can reduce pain and opioid use in adolescents and young adults after hip surgery. 64 participants will either receive the placebo plus usual care or usual care alone. The goal is to see if the pla…

This study tests whether starting physical therapy early after hip replacement, combined with electrical muscle stimulation and remote video coaching, helps people walk better and regain strength faster. About 52 adults aged 50-75 will be split into two groups: one gets the extra…

This study looks at whether injecting numbing medicine around the surgical cut can lower pain and the need for strong painkillers after a hip-preserving surgery called periacetabular osteotomy (PAO). About 120 people aged 13 to 50 with hip dysplasia will be split into three group…

This study tests whether a program of exercise and ergonomics training can reduce muscle and joint pain in teachers. About 80 teachers who have had pain for at least three months will be randomly assigned to receive the training or not. Researchers will measure changes in pain, d…

This study tests a web-based app called IAMABLE that provides evidence-based rehabilitation strategies for people with chronic conditions like heart disease, arthritis, or neurological disorders. Fifty adults aged 45 to 75 will use the app for 4 months to set goals and learn abou…

This study tests whether extra support for case managers helps veterans leaving the military better manage pain and reduce risky substance use. About 1800 veterans will take part. The program focuses on non-drug pain treatments and counseling.

This study uses computer models to compare four types of hip socket surgery in children aged 2 to 18 with hip dysplasia. Researchers will create 3D models from MRI scans and simulate each surgery to see how they change socket shape and volume. The goal is to understand which tech…

This study aims to learn more about rare skeletal disorders by collecting medical records, blood samples, and genetic data from 100 participants. People with known or suspected bone conditions, as well as their healthy family members, can join either remotely or in person. The go…

This observational study collects tissue samples from children undergoing surgery for polydactyly or hip dislocation, as well as from biobanks, to see which cells are best at forming cartilage. Researchers will test these cells in the lab and in animal models. The goal is to lear…

This study translates and tests several health questionnaires—covering pain, arm and leg function, mood, and daily activities—for use with Albanian-speaking people. Researchers will check if the translated versions are reliable and accurate by giving them to about 300 participant…

This study looks at how well a non-invasive navigation system helps surgeons place the hip cup during total hip replacement. About 118 people with hip conditions like arthritis or hip dysplasia will take part. The goal is to see if the actual cup position matches the planned posi…

This study is creating a collection of blood, urine, and leftover surgical tissue from 350 patients with bone, calcium, and growth plate disorders. The goal is to better understand how these diseases progress and to find markers that could predict outcomes. No new treatments are …

This study tests a new tool called the PRISM Dashboard, which gives physiotherapists feedback on how their decisions compare to their peers. The goal is to see if this feedback helps reduce differences in care for people with muscle and joint pain. About 60 physiotherapists and t…

This study follows 252 adults with muscle, bone, or joint problems (like arthritis, back pain, or after surgery) to see how well they do their prescribed home exercises. Researchers will track who sticks with the program and why, looking at factors like pain, mood, and support. T…

This study follows 2500 people who have had hip replacement surgery with Corin implants. Researchers will check how long the implants last and how well they work over 10, 15, and 20 years. The goal is to gather safety and performance data, not to test a new treatment.

This study tests whether using a virtual reality (VR) headset during shoulder exercises helps patients feel more engaged and motivated. Fifty adults with shoulder problems will do rehab exercises in a VR environment and then answer questionnaires about how easy and immersive the …

This study aims to create a secure national database for muscle and joint (musculoskeletal) conditions by collecting routine data from community clinics and GP practices. About 22,000 adults will have their information anonymously gathered to help develop a dashboard that tracks …

This study watches 2000 people having hip or knee replacement surgery to see how long spinal anaesthesia lasts. The goal is to learn how the amount of anaesthetic affects timing, helping doctors decide if patients can safely go home the same day. No new treatments are tested—just…

This study is testing whether adding hip arthroscopy to a standard hip realignment surgery (PAO) improves outcomes for people with hip dysplasia. About 204 participants will be randomly assigned to receive either PAO alone or PAO plus arthroscopy. Researchers will measure quality…

This study looks at how changing the heel cushion on an ankle-foot brace (AFO) affects walking in people who use one daily. Forty adults with leg injuries or nerve problems will try four different heel wedges—tall or short, soft or firm—while walking at controlled speeds. Researc…

This study looks at how 3D computer simulation and printing can help surgeons better plan and perform bone correction surgeries. Researchers will compare the planned corrections to the actual results in 100 children and young adults with rare bone deformities. The goal is to make…

This study follows 4,000 children who receive orthopedic implants (like rods or screws) during standard care for bone fractures, deformities, or hip problems. Researchers will track how long the implants last, any complications, and how well they work over time. The goal is to ga…

This study is building a registry of people with rare bone diseases (skeletal dysplasias) in Italy. Researchers will collect medical history, genetic data, and treatment details over time to better understand how these conditions progress. No experimental treatments are given; th…

This study follows 144 adults with muscle or bone problems who are already scheduled to receive treatment with Chattanooga Intelect devices (like TENS or ultrasound). Researchers will measure pain, muscle strength, and movement range to confirm the devices are safe and work as ex…