Dementia pugilistica
MONDO:0019976Conditions characterized by persistent brain damage or dysfunction as sequelae of cranial trauma. This disorder may result from diffuse axonal injury; intracranial hemorrhages; brain edema; and other conditions. Clinical features may include dementia; focal neurologic deficits; persistent vegetative state; akinetic mutism; or coma.
Also known as: Boxer's dementia, chronic traumatic encephalopathy, punch-drunk syndrome
14 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
-
Could your own stem cells heal your brain? new trial tests it
Disease control Recruiting nowThis study is testing whether stem cells taken from a person's own bone marrow and then given back through the veins and nose can improve brain and nerve function. It includes 500 people with various conditions like stroke, Parkinson's, Alzheimer's, and nerve damage. The goal is …
Phase: NA • Sponsor: MD Stem Cells • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
-
Viagra for the brain? new trial tests sildenafil in chronic TBI patients
Disease control Recruiting nowThis Phase 2 trial tests whether sildenafil citrate (the drug in Viagra) can improve blood vessel function in the brain of people who had a traumatic brain injury (TBI) at least 6 months ago. Researchers will give different doses (20, 40, or 80 mg) or a placebo to 160 adults aged…
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
-
New MRI scan aims to detect hidden brain injuries in soccer players
Diagnosis Recruiting nowThis pilot study is testing a new MRI technique called brainQuant to see if it can find early signs of brain damage in professional soccer players. Repeated headers may cause tiny brain injuries that lead to chronic traumatic encephalopathy (CTE). The study will scan 80 male socc…
Sponsor: University Hospital, Strasbourg, France • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
-
New streaming fitness platform aims to get brain injury survivors moving
Symptom relief Recruiting nowThis study is testing a new online exercise program made specifically for people with chronic brain injury. Researchers want to see if it helps them be more active and feel more confident about exercising. Sixty adults with chronic brain injury will take part; half will use the n…
Phase: NA • Sponsor: Ohio State University • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
-
Electric brain boost: new trial tests if zapping the scalp can fix Word-Finding problems after TBI
Symptom relief Recruiting nowThis study tests whether a technique called high-definition transcranial direct current stimulation (HD-tDCS) can improve word-finding difficulties in people who had a traumatic brain injury at least a year ago. The device delivers a very low electrical current through electrodes…
Phase: NA • Sponsor: Beth Israel Deaconess Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 07:55 UTC