Dementia pugilistica
MONDO:0019976Conditions characterized by persistent brain damage or dysfunction as sequelae of cranial trauma. This disorder may result from diffuse axonal injury; intracranial hemorrhages; brain edema; and other conditions. Clinical features may include dementia; focal neurologic deficits; persistent vegetative state; akinetic mutism; or coma.
Also known as: Boxer's dementia, chronic traumatic encephalopathy, punch-drunk syndrome
14 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Zapping the brain back to life: could DBS reawaken cognition after severe head trauma?
Disease control Not yet recruitingThis study tests whether deep brain stimulation (DBS) — a device that sends gentle electrical pulses to a key brain region — is safe and usable for people with chronic moderate to severe traumatic brain injury. Forty adults who are at least two years past their injury will receiv…
Phase: NA • Sponsor: ReEmerge, Inc. • Aim: Disease control
Last updated Jul 30, 2026 00:00 UTC
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Can a lifestyle program stop diabetes after brain injury?
Prevention Not yet recruitingThis study tests a one-year lifestyle program designed to help people with traumatic brain injury lose weight and prevent diabetes. The program includes 22 sessions over a year, focusing on healthy eating and physical activity. Researchers will track weight, blood pressure, and b…
Sponsor: Baylor Research Institute • Aim: Prevention
Last updated Jun 27, 2026 14:00 UTC
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Tiny study to watch MUSE stem cells in brain injury patients seeking treatment abroad
Knowledge-focused Not yet recruitingThis study will follow 10 people aged 6 to 75 with chronic traumatic brain injury who choose to get MUSE stem cell therapy outside the U.S. Researchers will not give any treatment but will track safety, brain function, and quality of life for 12 months. The goal is to gather real…
Sponsor: Healing Hope International • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC