Zapping the brain back to life: could DBS reawaken cognition after severe head trauma?
NCT ID NCT07730099
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This study tests whether deep brain stimulation (DBS) — a device that sends gentle electrical pulses to a key brain region — is safe and usable for people with chronic moderate to severe traumatic brain injury. Forty adults who are at least two years past their injury will receive the implant and be followed for three months. The goal is to see if the approach can improve thinking and daily function, starting with a careful check on safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Deep brain stimulation (DBS) — an implantable device that delivers continuous, low-voltage electrical pulses to deep brain regions.
- What this could lead to
- If safe and effective, this approach could offer a new way to improve cognitive function and daily living for people with long-term brain injury.
- What could go wrong
- This is a small, early feasibility study focused on safety, not proof of benefit. The surgical implantation carries risks like infection, bleeding, or hardware complications.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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