Decubitus ulcer

This trial tests a two-step treatment for chronic lower leg wounds that have not healed for over a month. First, a motorized waterjet cleans the wound, then a motion-based suction device applies negative pressure to promote healing. The study includes 50 adults with various types…

This study tests whether a repairing gel (Supraz) combined with a platelet-rich plasma-fibrin glue can eliminate odor and help heal chronic wounds that haven't improved with standard care. About 40 adults with a single wound lasting at least 3 months will receive either the new t…

This study tests whether adding a device that delivers mild electrical pulses (intermittent electrical stimulation) to standard care (turning patients every two hours) helps heal stage 1 or 2 bedsores on the lower back or tailbone. About 1,100 hospitalized adults will be randomly…

This early-stage study tests whether a person's own fat stem cells can safely help heal pressure ulcers or diabetic foot ulcers. Twelve adults will have a small amount of fat removed from their body, processed to extract stem cells, and then applied to their wound using a special…

This study looks at whether adding amniotic membrane products to standard wound care helps diabetic foot ulcers, venous leg ulcers, and pressure ulcers heal faster. Researchers will compare healing rates in 2,400 adults treated with these grafts versus those receiving standard ca…

This study looks at whether adding four types of amniotic membrane grafts to standard care helps heal chronic wounds like diabetic foot ulcers, venous leg ulcers, and pressure ulcers faster. Researchers will track 2,000 adults to see if wounds close completely within 12 weeks and…

This study tests whether a special lipid cream (EpiCeram) can prevent healed chronic wounds—like diabetic foot ulcers or pressure sores—from reopening. About 100 adults with recently healed wounds will apply either the cream or Vaseline for 3 months. Researchers will measure skin…

This study tests how accurately doctors, nurses, and technicians can diagnose ear barotrauma (pressure injury to the ear) using two different grading systems: the TEED score and the O'Neill Grading System (OGS). Thirty healthcare providers will grade 120 photos of eardrums to see…

This study compares a new device, cureVision cV, to an existing one (MolecuLight i:X) to see if it can accurately detect moderate to high levels of bacteria in wounds. About 100 adults with various wound types (like diabetic foot ulcers or surgical wounds) will be enrolled. The g…

This study tests a handheld device called the SEM Scanner that detects early skin damage up to 10 days before it's visible. Nursing home staff will use it during weekly skin checks to decide when to start prevention care. The goal is to reduce painful pressure injuries, especiall…

This study tests whether a topical oil made from palmitoleic acid can prevent pressure injuries (bedsores) in hospitalized adults at high risk. Sixty participants will apply the oil to their lower back four times daily for two weeks. Researchers will monitor skin moisture and oxy…

This study tests whether placing color-coded cards at the bedside of ICU patients can help nurses prevent pressure injuries (bedsores). The cards use red, yellow, and green to show high, medium, or low risk. Researchers will track 96 patients over 5 days to see if this simple vis…

This small study is testing Corplex P, a device made from donated human umbilical cord tissue, to see if it helps heal wounds that won't close on their own, like diabetic foot ulcers. Ten people will receive the device as part of their standard wound care. Researchers will track …

This study tests whether adding laser light therapy to standard wound care helps heal hard-to-heal ulcers in frail older adults receiving home healthcare. About 1,290 participants will receive the laser treatment on their wounds and nearby lymph areas. Researchers will track heal…

This study tests whether injecting platelet-rich plasma (PRP) directly into grade III ulcers can speed up healing. PRP is made from a small amount of the patient's own blood, processed to concentrate healing factors. Fifty adults with ulcers older than two weeks will receive eith…

This study looks at what intensive care nurses know and do to prevent pressure sores (bedsores). Researchers will survey and interview 60 nurses to find out their knowledge level and learn from their real-world experiences. The goal is to identify gaps in training and improve pat…

This observational registry will follow 5,000 adults with various wounds—like diabetic foot ulcers, burns, or surgical wounds—to see how different treatments (e.g., hydrocolloid, foam, silver dressings) perform in everyday medical settings. Researchers will measure wound healing,…

This study looks at whether artificial intelligence (AI) can match a dermatologist's diagnosis when a general practitioner sends in photos and questions about a patient's skin condition. Researchers will compare the AI's diagnosis to the dermatologist's for about 1000 adults. The…

This study looks at how low-level laser therapy (red light at 660 nm) affects the stiffness of chronic and burn wounds. Researchers will measure stiffness before and after a 3-minute laser treatment using two devices: OCT and MyotonPRO. The goal is to see if laser therapy changes…