Congenital temporomandibular joint ankylosis
MONDO:0016220Congenital temporomandibular joint ankylosis is a rare maxillofacial disorder characterized by significant reduction in mouth opening (i.e. from a few millimeters to a few centimeters) in the absence of acquired factors (e.g. trauma, infection) contributing to the ankylosis. It is associated with variable degrees of facial dysmorphism (i.e. lateral deviation of the mandible and chin, lower facial asymmetry, retrognathia, micrognathia, dental malocclusion) and patients typically present with feeding and breathing difficulties. Developmental delay, hypotonia, seizures, and additional dysmorphic features (e.g. pectus excavatum, low-set ears, hypoplastic alae nasi) have also been reported.
Also known as: congenital trismus
27 clinical trials for this condition and its sub-types.
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Knee implant study shows good function after two years
Disease control CompletedThis study looked at how well a specific knee replacement (balanSys UNI) works over time. 116 people with knee arthritis got the implant and were followed for at least 2 years. Doctors measured knee function using the Knee Society Score and checked X-rays for any problems.
Sponsor: Mathys Ltd Bettlach • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Can a gentle electrical patch ease jaw pain faster?
Symptom relief CompletedThis trial tests whether adding transcutaneous electrical nerve stimulation (TENS) to standard care—education, medication, and exercises—provides extra pain relief and better jaw function for people with temporomandibular disorders (TMD). About 48 adults with TMD will receive eit…
Phase: NA • Sponsor: Balikesir University • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Shining a light on jaw pain: could LED therapy offer Drug-Free relief for TMJ disorders?
Symptom relief CompletedThis trial tests whether shining red and infrared LED light on the jaw and neck muscles can reduce pain and improve movement in people with temporomandibular joint (TMJ) disorders. About 32 adults with TMJ pain will receive either real LED therapy or a placebo treatment over six …
Phase: NA • Sponsor: University of Nove de Julho • Aim: Symptom relief
Last updated Jul 31, 2026 00:00 UTC
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Stretching your way to better hips? pilot study tests the idea
Symptom relief CompletedThis pilot study looked at whether passive static stretching can increase hip flexibility in three groups: people who had hip replacement, those with long-term hip pain, and healthy volunteers. Twelve participants followed a 4-week stretching program three times a week under supe…
Sponsor: Omicron beta research • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Jaw pain breakthrough? three injections tested after TMJ procedure
Symptom relief CompletedThis study tested whether adding an injection of hyaluronic acid, platelet-rich fibrin, or dextrose to a standard jaw washout procedure (arthrocentesis) improves pain and jaw function more than the washout alone. Thirty-six adults with TMJ disorders who hadn't improved with other…
Phase: NA • Sponsor: Ondokuz Mayıs University • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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New splint adjustment technique could ease jaw pain for millions
Symptom relief CompletedThis study tested a specific technique for adjusting occlusal stabilizing splints used to treat temporomandibular disorders (TMD), which cause jaw pain and dysfunction. Researchers enrolled 800 patients with TMD and assessed their satisfaction after using the adjusted splints. Th…
Phase: NA • Sponsor: Mansoura University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Jaw pain relief at home: study tests virtual therapy
Symptom relief CompletedThis study tested whether physical therapy for temporomandibular disorders (TMD) — which cause jaw pain, headaches, and clicking — works just as well when done virtually (via video calls) as in person. Over 200 adults with TMD were split into two groups: one received standard in-…
Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Robot-Assisted knee surgery may outperform traditional methods
Symptom relief CompletedThis study compared robotic-assisted total knee replacement to the conventional technique in 95 patients with knee arthritis. The goal was to see if robotic surgery leads to better knee function, less pain, and higher satisfaction two years after the operation. Researchers also c…
Phase: NA • Sponsor: Hospital de Terrassa • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC