Congenital temporomandibular joint ankylosis
MONDO:0016220Congenital temporomandibular joint ankylosis is a rare maxillofacial disorder characterized by significant reduction in mouth opening (i.e. from a few millimeters to a few centimeters) in the absence of acquired factors (e.g. trauma, infection) contributing to the ankylosis. It is associated with variable degrees of facial dysmorphism (i.e. lateral deviation of the mandible and chin, lower facial asymmetry, retrognathia, micrognathia, dental malocclusion) and patients typically present with feeding and breathing difficulties. Developmental delay, hypotonia, seizures, and additional dysmorphic features (e.g. pectus excavatum, low-set ears, hypoplastic alae nasi) have also been reported.
Also known as: congenital trismus
27 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Can a cheaper plastic knee implant match the metal one in older adults?
Disease control TerminatedThis trial compares two types of knee replacement implants in people aged 75 and older: a standard metal-backed component and a cheaper all-polyethylene (plastic) one. The goal is to see if the all-polyethylene implant performs as well in terms of pain relief, movement, and how l…
Phase: NA • Sponsor: Maidstone & Tunbridge Wells NHS Trust • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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New surgical guides aim to help kids with locked jaws
Disease control OngoingThis study tests whether custom-made surgical guides can help surgeons safely and accurately treat children with a stiff or fused jaw joint (TMJ ankylosis). The approach uses a special saw to cut the bone precisely. Eight children under 15 are taking part, and the study checks ho…
Phase: NA • Sponsor: Alexandria University • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Hip implant under the microscope: 5-Year safety study launched
Knowledge-focused OngoingThis study is tracking 120 people who received a HYPE SCS hip stem during total hip replacement. Researchers will monitor how long the implant lasts, how satisfied patients are, and any complications over 5 years. The goal is to confirm the device is safe and works as intended in…
Sponsor: Societe dEtude, de Recherche et de Fabrication • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC