Jaw pain breakthrough? three injections tested after TMJ procedure
NCT ID NCT07479693
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding an injection of hyaluronic acid, platelet-rich fibrin, or dextrose to a standard jaw washout procedure (arthrocentesis) improves pain and jaw function more than the washout alone. Thirty-six adults with TMJ disorders who hadn't improved with other treatments took part. The goal was to see which, if any, of these add-on injections provides better relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Hyaluronic acid, injectable platelet-rich fibrin (i-PRF), and dextrose prolotherapy
What this could lead to
If one of these injections proves superior, it could offer a more effective, longer-lasting option for easing TMJ pain and improving jaw movement after a standard washout procedure.
What could go wrong
This is a small, completed trial with only 36 participants, so results may not apply to everyone. The study compared several treatments, and none may be clearly better than the standard procedure alone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ondokuz Mayis University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery
Samsun, Atakum, Turkey (Türkiye)