Cold urticaria
MONDO:0022799Cold urticaria is a condition that affects the skin. Signs and symptoms generally include reddish, itchy welts (hives) and/or swelling when skin is exposed to the cold (i.e. cold weather or swimming in cold water). This rash is usually apparent within 2-5 minutes after exposure and can last for 1-2 hours. The exact cause of cold urticaria is poorly understood in most cases. Rarely, it may be associated with an underlying blood condition or infectious disease. Treatment generally consists of patient education, avoiding exposures that may trigger a reaction, and/or medications.
Also known as: cold contact urticaria, primary idiopathic cold urticaria, urticaria idiopathic cold
10 clinical trials for this condition and its sub-types.
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New drug shows promise for Long-Term control of chronic hives
Disease control TerminatedThis study is testing the long-term safety and effectiveness of a drug called briquilimab for people with chronic hives. It includes 67 participants who have already completed a previous trial with the same drug. The goal is to see if briquilimab remains safe and helps control hi…
Phase: PHASE2 • Sponsor: Jasper Therapeutics, Inc. • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Experimental shot for Cold-Triggered hives tested, but trial stopped early
Symptom relief TerminatedThis early-stage trial tested a single dose of a drug called briquilimab in 27 adults with chronic hives caused by cold or friction that did not improve with standard allergy pills. The main goal was to check safety and see if the drug could reduce symptoms. However, the trial wa…
Phase: PHASE1, PHASE2 • Sponsor: Jasper Therapeutics, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC