Experimental shot for Cold-Triggered hives tested, but trial stopped early

NCT ID NCT06353971

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested a single dose of a drug called briquilimab in 27 adults with chronic hives caused by cold or friction that did not improve with standard allergy pills. The main goal was to check safety and see if the drug could reduce symptoms. However, the trial was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

chronic inducible urticaria Chronic Urticaria cold urticaria familial dermatographia immune system disorder Pruritus skin disorder skin vascular disease urticaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Charité - University Clinic Berlin

    Berlin, 12203, Germany

  • University Clinic Schleswig-Holstein

    Lübeck, 23538, Germany

  • University Hospital Dresden

    Dresden, 01307, Germany

  • University of Marburg

    Marburg, 35043, Germany

  • University of Munster

    Münster, 48149, Germany