New shot may stop hives from cold and scratching

NCT ID NCT07266402

Recruiting now Disease control Sponsor: Celldex Therapeutics Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 4 times

Summary

This study tests an investigational drug called barzolvolimab in 240 adults who get hives from cold temperatures or from scratching their skin, and whose symptoms are not controlled by standard allergy pills. Participants receive either the drug or a placebo injection, and doctors check if hives disappear after a cold or friction test at 12 and 24 weeks. The goal is to see if the drug can better control these chronic skin reactions.

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Conditions

The condition(s) this trial relates to.

chronic inducible urticaria cold urticaria familial dermatographia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC INDUCIBLE URTICARIA COLD URTICARIA COLD-INDUCED URTICARIA SYMPTOMATIC DERMOGRAPHISM

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

Addenbrooke's Hospital
NOT_YET_RECRUITING

Cambridge, United Kingdom
Advanced Clinical Research Institute
RECRUITING

Tampa, Florida, 33607, United States
Advanced Dermatology and Cosmetic Surgery - Spartanburg
RECRUITING

Spartanburg, South Carolina, 29307, United States
Advanced ENT and Allergy, PLLC
RECRUITING

Louisville, Kentucky, 40207, United States
Alergo-med Ośrodek Badań Klinicznych Sp. z o. o.
RECRUITING

Tarnów, Poland
Allergy & Asthma Consultants
RECRUITING

Redwood City, California, 94063, United States
Allergy & Immunology Unit, University of Cape Town Lung Institute
RECRUITING

Cape Town, South Africa
Allergy Associates of Utah
RECRUITING

Sandy City, Utah, 84093, United States
Allergy and Asthma Centre
RECRUITING

Westville, South Africa
Allergy, Asthma & Clinical Research Center
RECRUITING

Oklahoma City, Oklahoma, 73120, United States
Amicis Research Center
RECRUITING

Sherman Oaks, California, 91403, United States
CD8 Klinika
RECRUITING

Kaunas, Lithuania
Cahaba Dermatology & Skin Health Center, LLC
RECRUITING

Birmingham, Alabama, 35244, United States
Centricity Research Columbus Dermatology
RECRUITING

Columbus, Georgia, 31904, United States
Centrum Badań Klinicznych PI-House Sp. z o.o.
RECRUITING

Gdansk, 80-546, Poland
Centrum Medyczne ALL-MED Badania Kliniczne
RECRUITING

Krakow, Poland
Centrum Nowoczesnych Terapii Dobry Lekarz Sp. z o.o.
RECRUITING

Krakow, Poland
Cityclinic Przychodnia Lekarsko-Psychologiczna Matusiak Spolka Partnerska
RECRUITING

Wroclaw, Poland
Clinica Universidad de Navarra
RECRUITING

Pamplona, Spain
Deluxe Health Center, LLC
RECRUITING

Miami Lakes, Florida, 33014, United States
Department of Dermatology, University Hospital Dusseldorf
RECRUITING

Düsseldorf, Germany
Direct Helpers Research Center
RECRUITING

Hialeah, Florida, 33012, United States
Dr. PJ Sebastian
RECRUITING

Durban, South Africa
Elbe Kliniken Buxtehude Dermatologie
RECRUITING

Buxtehude, Germany
Endeavor Health Clinical Trials Center
RECRUITING

Skokie, Illinois, 60077, United States
Equity Medical, LLC
RECRUITING

Bowling Green, Kentucky, 42104, United States
Equity Medical, LLC
RECRUITING

New York, New York, 10023, United States
FOMAT - Allergy, Asthma & Immunology Medical Group
RECRUITING

Ventura, California, 93003, United States
Fraunhofer-Institut für Translationale Medizin und Pharmakologie ITMP Immunologie und Allergologie IA c/o Charité - Universitätsmedizin Berlin
RECRUITING

Berlin, Germany
GCP, Global Clinical Professionals
RECRUITING

St. Petersburg, Florida, 33705, United States
Global Clinical Trials (Pty) Ltd
RECRUITING

Pretoria, South Africa
Hautklinik, Uniklinkum Erlangen
NOT_YET_RECRUITING

Erlangen, Germany
Hospital del Mar
RECRUITING

Barcelona, Spain
Infinity Dermatology Inc
RECRUITING

Durban, South Africa
Johns Hopkins University
RECRUITING

Baltimore, Maryland, 21224, United States
Kern Research, Inc.
RECRUITING

Bakersfield, California, 93301, United States
Klinik und Poliklinik für Dermatologie und Allergologie, LMU Klinikum; DASZ-Dermato-Allergologisches Studienzentrum
RECRUITING

München, Germany
Klinika Ambroziak Dermatologia
RECRUITING

Warsaw, Poland
Luxderm Specjalistyczny Gabinet Dermatologiczny Prof. dr hab. N. med. Dorota Krasowska
RECRUITING

Lublin, Poland
MICS Centrum Medyczne Toruń
RECRUITING

Torun, Poland
MVZ DermaKiel GmbH
RECRUITING

Kiel, Germany
Markowitz Medical PLLC dba OptiSkin Medical
RECRUITING

New York, New York, 10128, United States
Medicome Sp. z o.o.
RECRUITING

Oświęcim, Poland
Newtown Clinical Research Centre
RECRUITING

Johannesburg, South Africa
Oddzial Kliniczny Chorob Wewnetrznych, Astmy i Alergii z Odcinkiem dla Dzieci, Uniwersytecki Szpital Kliniczny nr 1 w Lodzi
NOT_YET_RECRUITING

Lodz, Poland
One of a Kind Clinical Research Center
RECRUITING

Napa, California, 94558, United States
One of a Kind Clinical Research Center, LLC
RECRUITING

Scottsdale, Arizona, 85258, United States
Queen Elizabeth University Hospital
NOT_YET_RECRUITING

Glasgow, United Kingdom
RFSA Dermatology
RECRUITING

San Antonio, Texas, 78212, United States
Revival Research Institute, LLC
RECRUITING

Troy, Michigan, 48084, United States
Rosenpark Research GmbH
RECRUITING

Darmstadt, Germany
Salford Care Organisation NCA NHS Trust
NOT_YET_RECRUITING

Manchester, United Kingdom
Sandton Medical Research Centre
RECRUITING

Johannesburg, South Africa
Santa Familia PTG Lodz
RECRUITING

Lodz, Poland
Santaros KTC (klinikiniu tyrimu centras)
RECRUITING

Vilnius, Lithuania
Synapta Clinical Research Centre
RECRUITING

Durban, South Africa
Synexus Polska Sp. z o.o. Oddział w Gdańsku
RECRUITING

Gdansk, 80-382, Poland
Treasure Valley Medical Research
RECRUITING

Boise, Idaho, 83706, United States
UAB Alerginių susirgimų diagnostikos ir gydymo centras
RECRUITING

Vilnius, Lithuania
UAB Ausros Medicinos Centras
RECRUITING

Kaunas, Lithuania
University of Cincinnati
NOT_YET_RECRUITING

Cincinnati, Ohio, 45267, United States
Universitäts-Hautklinik Tübingen Studienzentrum Immundermatologie
RECRUITING

Tübingen, Germany
Universitätsklinikum Augsburg, Klinik für Dermatologie und Allergologie
RECRUITING

Augsburg, Germany
Universitätsklinikum Carl Gustav Carus Dresden, Klinik und Poliklinik für Dermatologie
RECRUITING

Dresden, Germany
Universitätsklinikum Göttingen -- George-August-Universitat Göttinggen, Klinik für Dermatoogie, Venerologie und Allergologie
RECRUITING

Göttingen, Germany
Universitätsklinikum Heidelberg, Klinik für Dermatologie
NOT_YET_RECRUITING

Heidelberg, Germany
Universitätsklinikum Münster, Klinik u. Poliklinik f. Dermatologie
RECRUITING

Münster, Germany
Universitätsklinikum Schleswig-Holstein Universität zu Lübeck - Campus Lübeck
RECRUITING

Lübeck, Germany
Uniwersytecki Szpital Kliniczny im. Fryderyka Chopina w Rzeszowie; Klinika Dermatologii i Dermatologii Onkologicznej
RECRUITING

Rzeszów, Poland
Uniwersytecki Szpital Kliniczny w Opolu
NOT_YET_RECRUITING

Opole, Poland
Well Pharma Medical Research, Corp.
RECRUITING

Miami, Florida, 33143, United States
Worthwhile Clinical Trials
RECRUITING

Benoni, South Africa

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