Cleft lip and alveolus

This trial tests whether adding a patient's own bone marrow concentrate to a bovine bone graft improves healing and bone regrowth in people born with a unilateral alveolar cleft. Half of the 16 participants receive the enriched graft, while the other half gets the standard bovine…

This study tested a new, simple device to reduce the size of wide gaps in the jawbone (alveolar clefts) in 15 people aged 12-25 with repaired cleft lip and/or palate. The device slowly pulls the bone together before a bone graft, aiming to make the graft more successful. The stud…

This study tested a new calcium phosphate putty to repair bone gaps in the gums of 84 children with unilateral cleft lip and palate. The putty was compared to the standard approach of using the child's own bone. Researchers measured how much bone remained after one year, as well …

This study tested a new method to repair a type of cleft palate that affects the upper gum (unilateral alveolar cleft). Ten patients received a 'sticky bone' graft combined with a special growth factor membrane. The researchers checked for inflammation, fluid leaking into the nos…

This study tested a special device placed inside the mouth to slowly pull bone across a wide gap in the gum (alveolar cleft) in 8 patients aged 7 to 20. The goal was to close the gap without needing a bone graft. Researchers measured changes in the cleft size, tooth movement, and…

This study tested two different bone graft materials to repair a common birth defect called alveolar cleft (a gap in the upper jaw). Fourteen children aged 8 to 12 received either a standard graft or one mixed with a special blood product. The goal was to see which material led t…

This trial tests whether stem cells from children's shed baby teeth can replace the standard hip bone graft for repairing a cleft in the upper jaw. Twenty children aged 7 to 12 with cleft lip and palate will receive either the stem cell graft or a traditional bone graft from thei…

This completed study looked at 111 newborns who had cleft lip repair surgery. Researchers compared those who received a regional nerve block for pain relief to those who did not. The goal was to see if the nerve block reduced the amount of opioid pain medicine needed during and a…