Cholelithiasis

This trial tests whether a procedure called EUS-guided gallbladder drainage can prevent future gallbladder attacks in people who are too sick or frail for surgery. Participants are randomly assigned to receive either the drainage procedure or standard medical care. The study will…

This study will follow 220 patients with benign gallbladder diseases who cannot have surgery. It compares two non-surgical approaches: endoscopic drainage with possible stone removal versus traditional drainage alone. The goal is to see which method leads to fewer complications a…

This trial tests whether a TAP block, an injection of local anesthetic into the abdominal wall, can reduce pain after laparoscopic gallbladder surgery. Researchers will compare 200 patients who receive the block with those who do not, measuring pain scores, painkiller use, and ho…

This study tests whether a specific nerve block, called the rectointercostal plane block (RICPB), can reduce pain and the need for strong painkillers after gallbladder removal surgery. Sixty adults scheduled for laparoscopic cholecystectomy will receive either the RICPB or standa…

This study compares two types of nerve blocks—erector spinae plane block and subcostal transversus abdominis plane block—for pain after laparoscopic gallbladder removal. One hundred adults having elective surgery will receive one of the two blocks, and researchers will track how …

This study tests a special oxygen tube placed in the mouth during a procedure called ERCP, which is used to treat bile duct and pancreas problems. The goal is to see if this method can prevent low oxygen levels that often happen when patients are deeply sedated. About 410 adults …

This study compares two common pain relief techniques after laparoscopic gallbladder removal: local anesthetic injected into the surgical cuts versus an ultrasound-guided nerve block near the belly button. The goal is to see which method better reduces pain and the need for opioi…

This study tests whether watching educational videos about early movement before and after gallbladder surgery can improve recovery. 44 adults scheduled for laparoscopic gallbladder removal will either receive standard care or standard care plus video-guided mobilization training…

This study tests whether a nerve block called the erector spinae plane (ESP) block can reduce pain and help patients breathe better after laparoscopic gallbladder removal. 70 adults having elective surgery will be randomly assigned to receive either the ESP block plus standard pa…

This study tests whether giving lidocaine through an IV during gallbladder surgery can reduce inflammation and pain, and help the gut start working again sooner. 90 adults having planned laparoscopic gallbladder removal will be randomly assigned to receive either lidocaine or a p…

This study investigates whether two specific gene variants (ABCG8 and UGT1A1) are linked to gallstone disease that requires gallbladder removal after bariatric surgery. Researchers compare adults who had weight-loss surgery and later needed their gallbladder removed with those wh…

This study will observe 165 adults having laparoscopic gallbladder surgery to compare three different intubation techniques. Researchers will track how often patients have a sore throat, cough, or hoarseness after surgery. No extra medications or procedures are given—just standar…