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Can a simple injection replace opioids after gallbladder surgery?

NCT ID NCT07800624

Symptom relief Sponsor: Jinnah Postgraduate Medical Centre Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

This trial tests whether a TAP block, an injection of local anesthetic into the abdominal wall, can reduce pain after laparoscopic gallbladder surgery. Researchers will compare 200 patients who receive the block with those who do not, measuring pain scores, painkiller use, and hospital stay length. The goal is to see if this nerve block offers better pain control and fewer opioid side effects.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
A TAP block, an injection of local anesthetic into the abdominal wall to numb nerves and reduce pain after surgery
What this could lead to
If it works, this could offer a simple way to better control pain after gallbladder surgery, reduce the need for opioid painkillers, and shorten hospital stays.
What could go wrong
This is a single-center trial, and results may not apply to other settings. The block may not reduce pain enough to make a meaningful difference, and there are small risks from the injection itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with symptomatic cholelithiasis and advised to undergo laparoscopic cholecystectomy. * Both Genders * Age more than 10 years and not above 60 years. Exclusion Criteria: * Patients with contraindications for surgery. * Patients below the age of 10 years or above 60 years.

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Conditions

The condition(s) this trial relates to.

cholelithiasis Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cholecystectomy, laparoscopic Tap block

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Jinnah postgraduate medical university

    Karachi, Sindh, 75500, Pakistan

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