New nerve block aims to cut opioid use after gallbladder surgery

NCT ID NCT07676552

Not yet recruiting Symptom relief Sponsor: Koç University Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 02, 2026 · Updated 2 times

Summary

This study tests whether a specific nerve block, called the rectointercostal plane block (RICPB), can reduce pain and the need for strong painkillers after gallbladder removal surgery. Sixty adults scheduled for laparoscopic cholecystectomy will receive either the RICPB or standard local anesthetic at the surgical sites. Researchers will measure pain scores and total morphine use over the first 24 hours after surgery to see which approach works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine
What this could lead to: If effective, this nerve block could become a standard way to manage pain after gallbladder surgery, reducing the need for strong painkillers.
What could go wrong: This is a small, early-stage trial with 60 participants, so results may not apply to everyone. The block may not provide better pain relief than current methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cholelithiasis Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHOLELITHIASIS POSTOPERATIVE PAIN

Contacts and locations

Locations

Koç University Hospital

Istanbul, Istanbul, 34010, Turkey (Türkiye)

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