CHOLELITHIASIS

This study looks at whether older adults (80+ or 75+ with health issues) benefit more from gallbladder removal surgery or simply monitoring after their bile duct stones are cleared. About 400 participants will be followed for a year to compare deaths, major complications, and ret…

This trial looks at whether removing the gallbladder early (during the same hospital stay) or waiting 4 weeks after recovery is better for people with severe pancreatitis caused by gallstones. About 134 adults will be randomly assigned to one of the two timing options. The main g…

This trial compares two drugs used to put people to sleep for gallbladder surgery: remimazolam and propofol. Researchers measure how quickly each drug causes loss of consciousness and check for side effects like low blood pressure. Participants are healthy adults aged 18–50 under…

This study will test whether giving dexamethasone, dexmedetomidine, or both right after gallbladder surgery helps the gut start working again sooner. 160 adults having laparoscopic gallbladder removal will be randomly assigned to one of four groups, including a placebo. The main …

This study compares two ultrasound-guided nerve blocks to control pain after laparoscopic gallbladder removal. Seventy adults will receive either a modified thoracoabdominal nerve block or a recto-intercostal fascial plane block. The goal is to see which block reduces the need fo…

This study tests whether having patients keep a pain diary after gallbladder surgery helps them report their pain more accurately than standard methods. About 142 adults having laparoscopic gallbladder removal will either use a diary or receive usual care. The goal is to improve …

This study compares two ways to manage pain after laparoscopic gallbladder removal. One group gets standard local anesthesia at the incision sites, while the other also receives a nerve block guided by the surgery camera. The goal is to see if the added block reduces pain and the…

This study compares two common anesthesia gases, sevoflurane and desflurane, to see which one puts less strain on the lungs during gallbladder removal surgery. Researchers will measure lung mechanics at three points during the operation in 138 adults. The goal is to find out if o…

This study is testing whether a camera can accurately measure heart rate, blood pressure, and oxygen levels by recording a patient's face during surgery. The goal is to replace some of the sticky sensors and cuffs that touch the skin, which can cause infections or injuries in fra…

This study looks back at the records of 2,000 adults who had liver surgery with their gallbladder left in place. Researchers want to know if a technique called the Pringle maneuver, which temporarily stops blood flow to the liver during surgery, increases the chance of developing…