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Which anesthesia gas is easier on the lungs? new trial aims to find out

NCT ID NCT07295158

Knowledge-focused Sponsor: Konya City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 16, 2026 · Updated 7 times

Summary

This study compares two common anesthesia gases, sevoflurane and desflurane, to see which one puts less strain on the lungs during gallbladder removal surgery. Researchers will measure lung mechanics at three points during the operation in 138 adults. The goal is to find out if one gas is safer for breathing, which could help guide future anesthesia choices.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sevoflurane and desflurane (anesthetic gases)
What this could lead to
If it works, this could help anesthesiologists choose the safer gas for lung health during surgery.
What could go wrong
This is a small, early-stage study focused on a short-term breathing measurement, not long-term outcomes. Results may not apply to sicker or heavier patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

138 people

The number who actually took part.

Started

Mar 2026

Finished

Sep 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-65 years ASA Physical Status I-II Scheduled for elective laparoscopic cholecystectomy Able to provide written informed consent Exclusion Criteria: Known hypersensitivity or contraindication to study medications (sevoflurane or desflurane) Severe chronic obstructive pulmonary disease (COPD) Uncontrolled bronchial asthma Decompensated heart failure (NYHA Class III-IV) History of prior lung surgery Morbid obesity (BMI \> 35 kg/m²) Pregnancy Refusal to participate or inability to provide informed consent \-

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Conditions

The condition(s) this trial relates to.

cholelithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Perioperative respiratory mechanics

Contacts and locations

Locations

  • Konya City Hospital

    Konya, Konya, 42020, Turkey (Türkiye)

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